Inhouse product
Indications
Citapram is indicated
for-
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Pharmacology
Citalopram is bicyclic
phthalane derivative and a selective serotonin re-uptake inhibitor, with little
or no effect on noradrenaline, dopamine and GABA re-uptake. The inhibitory
activity explains the antidepressant property of citalopram. It has no or very
low affinity for 5-HT1AA, 5-HT2A, D1 and
D2 receptors, α1, α2, β-adrenergic,
histamine H1, muscarinic, cholinergic, benzodiazepine and opioid
receptors.
Dosage &
Administration
Depressive illness:
Panic disorder:
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Interaction
Citapram should not be
taken cocurrently with MAOIs, Serotonin agonists, Neuroleptics, Cimetidine,
Alcohol, Ketoconazole, Itraconazole, Macrolide antibiotics.
Contraindications
Citalopram should not
be used if the patient enters a manic phase.
Side Effects
Palpitation, postural
hypotension, coughing, yawning, confusion, impaired concentration, amnesia,
migraine, taste disturbance, increased salivation, rhinitis, tinnitus,
micturition disorders.
Pregnancy &
Lactation
Pregnancy: There are on adequate and well-controlled
studies in pregnant women; therefore, Citalopram should be used during
pregnancy only if the potential benefit justifies the potential risk to the
fetus.
Lactation: Citalopram is excreted in human breast milk.
So, the decision whether to continue or discontinue either nursing or
Citalopram therapy should take into account the risks of Citalopram exposure
for the infants and the benefits of Citalopram treatment for the mother.
Precautions &
Warnings
Citapram should be
used with caution in patients with epilepsy, concurrent electroconvulsive
therapy, history of mania, cardiac disease, diabetes mellitus, angle-closure
glaucoma, history of bleeding disorders, hepatic and renal impairment,
pregnancy and breast feeding.
Overdose Effects
Doses as high as 2000
mg have been taken without signs of alternation in cardiovascular parameters.
Respiratory depression, convulsion may occur.
Therapeutic Class
SSRIs & related
anti-depressant drugs
Storage Conditions
Keep below 30°C temperature, away from light
& moisture. Keep out of the reach of children.
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