Indications

Eye/Ear/Nasal solution: This is indicated for dry nasal membranes including dry nose resulting from cold and allergy medications. It moistens dry nasal passages from dry climates or from airplane travel, may help dissolve mucus from study noses and clears the nose after surgery. This sterile saline solution is also used to cleanse various parts of the body (wounds, body cavities) and medical equipment (e.g. bandages, catheters, drainage tubes). It is also used as a mixing solution (diluent) for other medications used to irrigate the body (e.g. bacitracin, polymyxin).

Intravenous Solution: For instance, in the management of metabolic alkalosis, in case of gastro-enteritis, during and after surgery. It may also be used as a priming fluid for haemodialysis procedures. Happysol 0.9% infusion is often used as diluents for infusion of drug additives etc. It is widely used for sterile irrigation and dilution process.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Pharmacology

Nasal drop: Sodium Chloride nasal drop is a non-drug, isotonic saline solution that is used to moisturize nasal membranes. This formulation provides comfort for extensive and continuous use. Sodium Chloride 0.9% nasal wash moistures inside the nose by dissolving and softening thick or crusty mucus thus helps to remove the mucus from the nose and makes breathing easier. Excess sodium is predominantly excreted by the kidneys with small amounts lost in faeces and sweat.

Nasal spray: Sodium Chloride 0.9% Nasal Spray moistens inside the nose by dissolving and softening thick or crusty mucus thus helps to remove the mucus from the nose and makes breathing easier. Excess Sodium is predominantly excreted by the kidneys with small amount lost in faeces and sweat. In babies and young children with stufy noses who cannot blow their noses, using this product helps to make the mucus easier to remove with a nasal bulb syringe. This helps relieve stufness and makes breathing easier.

Dosage

Nasal drop-

• Nasal Congestion: In infants, 1-2 drops of Sodium Chloride nasal wash in each nostril before feeds will help relieve congestion and allow more effective suckling.
• Ear Wax Removal: Allow the Sodium Chloride nasal wash to warm to room temperature before use. It is important to put the drops into the ear carefully. Lie down on one side and fill the ear canal with the drops and wait for a few minutes before standing up. Age: from 6 months onwards. Put 3 to 4 drops into the affected ear(s) 3 to 4 times a day for 3 to 5 days.

Nasal Spray-

• Newborn to 12 months: 1 spray into each nostril for 2-3 times or as directed by the physician.
• Children over 12 months & Adults: 1 to 2 sprays into each nostril for 2-3 times or as directed by the physician.

For eye use: 1 or 2 drops in each eye when needed.

For ear use: 3 to 4 drops into the affected ear(s) 3 to 4 times a day for 3 to 5 days.

Intravenous Solution: The concentration and dosage of Sodium Chloride solution for intravenous use is determined by several factors including age, weight and clinical condition of the patient. Usually, the adult dose is about 1000 ml of 0.9% injection.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Administration

How to use the Nasal Spray-

• Shake the bottle gently and remove the dust cover.
• Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
• Gently blow the nose to clear the nostrils.
• Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar of nasal applicator firmly down once to release a spray.
• Breathe out through your mouth.
• Repeat the above steps in the same/ other nostril for consecutive doses.

Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-

• Remove the dust cover.
• Gently pull off the nasal applicator.
• Wash the applicator and dust cover in warm water.
• Shake off the excess water and leave to dry in a normal place. Avoid to apply additional heat.
• Gently push the applicator back on the top of the bottle and re-fix the dust cover.

How to use Intravenous Solution-

• Check infusion set and infusion solution prior to use.
• Pull moderately to tear off the protective cover of the Eurocap.
• Hold lightly the Eurocap but not the bottle body.
• Open the flow regulator fully and hold the giving set on the top white area, but not the memorane venting region.
• Insert the spike of the administration set to the Eurocap and fit the connector of the administration set firmly to the needle.
• Gradually allow the fluid to flow down to the needletip and close.
• Remove the protective cover of the needle.
• Locate the venpuncture site and clean the site with an antiseptic solution, and then insert the needle.
• Securely tape the puncture site.
• Securely tape the wings and tubing
• Start infusion while adjusting drip speed.

* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'

Contraindications

Do not share this medication with others. Doing so may increase the risk of infection.

Side Effects

Eye/Ear/Nasal: No side effects are expected to occur. However stinging, sneezing, increased nasal discharge, or salty taste may occur in some cases.

Intravenous: Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation, and hypervolemia. If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Pregnancy & Lactation

Eye/Ear/Nasal: Tell your doctor if you are pregnant before using this medication. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.

Intravenous: Pregnancy Category C. Animal reproductive studies have not been conducted with Sodium Chloride Injection USP 0.9%. It is also not known whether Sodium Chloride Injection USP 0.9% can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Sodium Chloride Injection USP 0.9% should be given to a pregnant woman only if clearly needed.

Precautions & Warnings

Eye/Ear/Nasal: Tell your doctor about your medical history, especially of heart problems (e.g., congestive heart failure), lung problems (pulmonary edema), kidney problems, low levels of potassium (hypokalemia), high levels of sodium (hypernatremia), and any allergies.

Intravenous: Serum electrolyte concentration should be carefully monitored. Happysol should be administered with caution to patients with congestive heart failure, peripheral or pulmonary oedema, impaired renal function or pre-eclampsia. Care should also be taken when administering Happysol intravenously to very young or elderly patients. Excessive administration should be avoided as this may result in hypokalaemia. Infusion of fluid should be immediately discontinued if rigor arises for any reason during its application. Do not use if the solution is cloudy, contains particles, or after expiry date.

Overdose Effects

There have been no adverse reports of overdose with Happysol 0.9% nasal wash.

Therapeutic Class

Intravenous fluid preparations, Nasal Decongestants & Other Nasal Preparations

Storage Conditions

Keep out of the reach of children. Store at room temperature (between 15°C to 30°C), away from light and moisture.