Inhouse product
Indications
This is indicated for
the eradication of H. pylori in active chronic gastric, duodenal and gastric
ulcers.
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Pharmacology
Lansoprazole is a
proton-pump inhibitor which inhibits the stomach's production of gastric acids.
Amoxicillin is a penicillin antibiotic. It acts by inhibiting the synthesis of
bacterial cell walls.lt inhibits cross-linkage between the linear peptidoglycan
polymer chains that make up a major component of the cell walls of both
Gram-positive and Gram-negative bacteria. Clarithromycin is a macrolide
antibiotic.It prevents bacteria from growing by interfering with their protein
synthesis. It binds to the subunit 50S of the bacterial ribosome and thus
inhibits the translation of peptides
Dosage & Administration
Adult dose: One strip twice daily for 7-14 days or as
per the physician's advice.
Geriatric use: Elderly patients may suffer from
asymptomatic renal and hepatic dysfunction. Care should be taken when
administering to these patients.
* রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Interaction
Contraindications
This is
contraindicated in patients with known hypersensitivity to any of its
component.
Side Effects
Adverse reactions
which were reported as possibly or probably related to treatment (>3%) in
clinical trials when all three components of this therapy were given
concomitantly are listed below and divided by body systems. Digestive system:
Nausea, vomiting, diarrhea, dark stools, dry mouth, glossitis, oral moniliasis,
stomatitis, tongue discoloration. Musculoskeletal System: myalgia. Nervous
System: confusion, headache, dizziness; Skin: skin reactions. Urogenital
System: vaginitis,vaginal moniliasis.
Pregnancy & Lactation
There were no adequate
and well-controlled studies in pregnant women. This should be used during
pregnancy only if the potential benefit justifies the potential risk of the
mother. Amoxicillin is excreted in human milk in very small amounts. Because of
the potential for serious adverse reactions in nursing infants. A decision
should be made whether to discontinue nursing or to discontinue the drug
therapy, taking into account the importance of the therapy to the mother.
Precautions & Warnings
Serious and
occasionally fatal hypersensitivity (anaphylactoid) reactions have been
reported in patients on Amoxicillin therapy. These reactions are more
appropriate to occur in individuals with a history of penicillin
hypersensitivity. Clarithromycin should not be used in pregnant women except in
clinical circumstances where no alternative therapy is appropriate.
Therapeutic Class
Anti H. pylori drugs
Storage Conditions
Store in a cool and
dry place, protected from light.
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