Dicephin Injection 250 mg/vial contains Ceftriaxone Sodium 250 mg, a third-generation cephalosporin antibiotic with broad-spectrum activity. Ceftriaxone is a highly potent antibiotic used to treat a wide range of bacterial infections, including serious and life-threatening conditions. It works by inhibiting bacterial cell wall synthesis, leading to the death of susceptible bacteria. Dicephin Injection is suitable for both pediatric and adult patients and can be administered intramuscularly (IM) or intravenously (IV) depending on the clinical condition.

Ceftriaxone is known for its long half-life, which allows for convenient once or twice-daily dosing. It is highly effective against gram-positive and gram-negative bacteria, including strains resistant to earlier-generation cephalosporins. Dicephin Injection is particularly useful in hospital settings for the treatment of severe infections where rapid, reliable antibacterial activity is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dicephin Injection 250 mg/vial is indicated for the treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections: pneumonia, bronchitis, and severe lower respiratory infections

• Ear, nose, and throat infections: otitis media, sinusitis, and pharyngitis

• Skin and soft tissue infections: cellulitis, abscesses, and wound infections

• Urinary tract infections: cystitis, pyelonephritis, and complicated infections

• Bone and joint infections under medical supervision

• Septicemia and bacteremia caused by susceptible organisms

• Gonorrhea and other sexually transmitted infections caused by susceptible strains

• Surgical prophylaxis to prevent postoperative infections in high-risk procedures

Dicephin should be used only for confirmed or strongly suspected bacterial infections to prevent resistance.

Dosage and Administration

The dosage of Dicephin Injection 250 mg/vial should be determined by a qualified healthcare professional based on the patient’s age, weight, infection type, severity, and kidney function:

• Adults: Typically 250 mg to 1 g daily, either as a single dose or divided doses; severe infections may require higher doses

• Children: Dose calculated according to body weight, typically 50–75 mg/kg/day divided once or twice daily

• Reconstitute the vial with a suitable diluent as per the manufacturer’s instructions

• Administer via intravenous infusion or intramuscular injection; slow IV injection is recommended for safety

• Complete the full prescribed course, even if symptoms improve early, to prevent recurrence and resistance

Precautions

• Contraindicated in patients with known hypersensitivity to ceftriaxone, other cephalosporins, or penicillin

• Use cautiously in patients with severe renal or hepatic impairment

• Monitor for signs of superinfection during prolonged therapy

• Avoid mixing with calcium-containing solutions in neonates due to risk of precipitation

• Inform the physician about other medications, particularly anticoagulants or nephrotoxic drugs

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Dicephin Injection is generally well tolerated, but side effects may occur:

• Local reactions at injection site: pain, redness, or swelling

• Gastrointestinal disturbances: diarrhea, nausea, vomiting

• Allergic reactions: rash, itching, urticaria, or rarely anaphylaxis

• Hematologic changes: transient eosinophilia or neutropenia in prolonged therapy

• Rare liver enzyme elevation or biliary sludging

Seek immediate medical attention if severe allergic reactions, persistent diarrhea, or jaundice occur.

Storage

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Dicephin Injection 250 mg/vial provides effective, broad-spectrum antibacterial therapy for serious bacterial infections, ensuring rapid and reliable clinical response under professional supervision.