HB-fix Injection 20 mcg/ml is a recombinant DNA vaccine used for the prevention of Hepatitis B infection. It contains a purified antigen produced using genetic engineering techniques and helps the body develop immunity against the Hepatitis B virus.

It is a preventive vaccine and not used to treat active infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each dose contains:

• Hepatitis B surface antigen (rDNA) 20 mcg

For intramuscular injection only.

Mechanism of Action

HB-fix vaccine works by:

• Introducing a non-infectious hepatitis B surface antigen (HBsAg) into the body
• Stimulating the immune system to produce protective antibodies
• Creating long-term immune memory against Hepatitis B virus
• Providing protection without causing the disease

After full vaccination, the body is able to quickly respond if exposed to the virus.

Indications

HB-fix Injection is indicated for:

• Prevention of Hepatitis B
• Newborn immunization (as part of routine vaccination schedule)
• Healthcare workers and laboratory staff at risk of exposure
• Individuals with chronic liver disease or kidney disease
• Patients undergoing hemodialysis
• People at increased risk due to lifestyle or exposure

Dosage and Administration

• Given as an intramuscular injection (usually in the deltoid muscle in adults)
• Administered as a 3-dose series (0, 1, and 6 months) or as per immunization schedule
• Dose and schedule may vary based on age and risk factors
• Booster doses may be recommended in some high-risk individuals

Benefits

HB-fix Injection provides:

• Effective long-term protection against Hepatitis B infection
• Reduces risk of chronic liver disease and liver cancer
• Safe and well-tolerated vaccine
• Important preventive measure in healthcare settings
• Forms part of national immunization programs

Possible Side Effects

Common side effects include:

• Pain or redness at injection site
• Mild fever
• Fatigue
• Headache

Less common side effects:

• Swelling at injection site
• Nausea
• Muscle aches

Serious side effects (rare):

• Anaphylaxis
• Severe hypersensitivity reactions

Precautions

• Not used for treatment of active Hepatitis B infection
• Inform doctor of any severe allergy history
• Use cautiously in individuals with fever or acute illness
• Complete full vaccine schedule for effective protection
• Monitor briefly after injection for allergic reactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• Generally no significant drug interactions
• May be given with other vaccines at different injection sites

Storage

• Store in a refrigerator at 2°C–8°C
• Do not freeze
• Protect from light
• Shake gently before use if required