Hemadus Tablet 20 mg contains roxadustat, an oral medication used for the treatment of anemia associated with chronic kidney disease (CKD). It helps stimulate natural red blood cell production in the body, improving hemoglobin levels and reducing symptoms such as fatigue, weakness, and shortness of breath. This low-dose strength is typically used for dose initiation or fine adjustment in individualized therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Roxadustat 20 mg
• Dosage Form: Oral tablet

Mechanism of Action

Roxadustat is a hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor. It works by stabilizing hypoxia-inducible factors (HIF), which increases endogenous erythropoietin production from the kidneys and liver. It also enhances iron absorption and utilization by reducing hepcidin levels, thereby supporting effective red blood cell formation and improving oxygen delivery in the body.

Indications

Hemadus Tablet 20 mg is indicated for:

• Anemia due to chronic kidney disease (CKD) in non-dialysis patients
• Anemia in dialysis-dependent CKD patients
• Low hemoglobin levels associated with impaired kidney function
• Dose titration and individualized anemia management therapy

Dosage and Administration

• Dosage is strictly individualized based on hemoglobin levels and clinical response
• Commonly administered 3 times per week or as directed by a physician
• Can be taken with or without food
• Regular monitoring of hemoglobin, iron status, and blood pressure is required
• Dose adjustments must only be made under medical supervision

Benefits

• Helps increase hemoglobin levels naturally
• Reduces symptoms of anemia such as tiredness and weakness
• Improves iron utilization in the body
• Oral therapy offers convenience compared to injections
• Supports long-term management of CKD-related anemia

Possible Side Effects

Common side effects may include:

• Nausea
• Dizziness
• Headache
• Swelling (edema)
• Increased blood pressure

Serious side effects may include:

• Risk of blood clots (thromboembolic events)
• Cardiovascular complications
• Severe hypertension
• Abnormal liver function tests

Precautions and Warnings

• Regular monitoring of hemoglobin and blood pressure is essential
• Use cautiously in patients with cardiovascular disease
• Not recommended during pregnancy or breastfeeding unless prescribed
• Iron deficiency should be corrected before and during treatment
• Must be used only under strict medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Hemadus Tablet 20 mg (Roxadustat) is an effective low-dose oral therapy for anemia associated with chronic kidney disease. It supports natural red blood cell production and improves hemoglobin levels, helping reduce anemia-related symptoms when used under proper medical supervision.