Olmepin Tablet is a combination antihypertensive medicine containing Amlodipine Besilate and Olmesartan Medoxomil. It is used for the treatment of high blood pressure (hypertension). This fixed-dose combination works through dual mechanisms to provide stronger and more consistent blood pressure control in patients who require combination therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Amlodipine Besilate 5 mg
• Olmesartan Medoxomil 40 mg

Indications

Olmepin Tablet is indicated for:

• Essential hypertension (high blood pressure)
• Patients not adequately controlled with single-agent therapy
• Reduction of risk of cardiovascular events such as heart attack and stroke
• Long-term management of moderate to severe hypertension

Mechanism of Action

This combination acts through two complementary pathways:

• Amlodipine, a calcium channel blocker, relaxes vascular smooth muscles by inhibiting calcium influx, leading to vasodilation and reduced blood pressure.
• Olmesartan, an angiotensin II receptor blocker (ARB), blocks vasoconstriction caused by angiotensin II, further lowering blood pressure.

Together, they provide enhanced and sustained antihypertensive effects.

Dosage and Administration

• Take as prescribed by a physician
• Usually taken once daily at the same time each day
• Can be taken with or without food
• Swallow the tablet with water
• Regular monitoring of blood pressure is recommended

Benefits

• Provides strong and effective blood pressure control
• Reduces risk of heart attack, stroke, and kidney complications
• Dual mechanism ensures better therapeutic response
• Helps improve overall cardiovascular health
• Convenient once-daily dosage

Side Effects

Common side effects may include:

• Dizziness
• Headache
• Swelling of ankles or feet (due to amlodipine)
• Fatigue
• Nausea

Serious but rare side effects include:

• Severe hypotension (low blood pressure)
• Kidney function impairment
• High potassium levels (hyperkalemia)
• Allergic reactions

Seek immediate medical attention if severe symptoms occur.

Precautions and Warnings

• Use cautiously in patients with liver or kidney disease
• Monitor blood pressure, kidney function, and electrolytes regularly
• Not recommended during pregnancy (risk to fetus)
• Use during breastfeeding only if advised by physician
• Avoid dehydration during therapy

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Olmepin Tablet may interact with:

• Other antihypertensive medications
• Potassium supplements or potassium-sparing diuretics
• NSAIDs (may reduce antihypertensive effect and affect kidney function)
• Lithium (risk of toxicity)
• Simvastatin (amlodipine may increase levels)

Always inform your healthcare provider about all medications being used.

Storage

• Store below 30°C in a cool and dry place
• Protect from light and moisture
• Keep out of reach of children.