Pregel Tablet 40 mg contains pantoprazole sodium, a proton pump inhibitor (PPI) used to reduce excessive stomach acid production. It is commonly prescribed for acid-related gastrointestinal disorders such as gastroesophageal reflux disease (GERD), peptic ulcers, and gastritis. This higher-strength formulation is used in more severe or resistant acid-related conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Pantoprazole Sodium 40 mg
• Dosage Form: Oral tablet (enteric coated)

Mechanism of Action

Pantoprazole works by selectively blocking the hydrogen-potassium ATPase enzyme (proton pump) in the gastric parietal cells. This enzyme is responsible for the final step of acid secretion in the stomach. By inhibiting it, pantoprazole significantly reduces gastric acid production, helping relieve symptoms and promote healing of acid-related damage.

Indications

Pregel Tablet 40 mg is indicated for:

• Gastroesophageal reflux disease (GERD)
• Peptic ulcer disease (gastric and duodenal ulcers)
• Erosive esophagitis
• Zollinger-Ellison syndrome (as prescribed)
• Prevention of NSAID-induced gastric ulcers

Dosage and Administration

• Usually taken once daily before meals
• Swallow the tablet whole with water; do not crush or chew
• Dosage and duration depend on the severity of the condition
• Follow physician instructions strictly for best results

Benefits

• Provides strong and long-lasting acid suppression
• Relieves heartburn and acid reflux symptoms
• Promotes healing of ulcers and esophageal inflammation
• Protects stomach lining from acid damage
• Improves overall digestive comfort

Possible Side Effects

Common side effects may include:

• Headache
• Nausea
• Abdominal pain
• Diarrhea or constipation
• Flatulence

Less common but serious side effects may include:

• Vitamin B12 deficiency (with long-term use)
• Low magnesium levels
• Increased risk of bone fractures with prolonged use
• Allergic reactions

Precautions and Warnings

• Long-term use should be monitored by a physician
• Use cautiously in patients with liver impairment
• May interact with certain medicines (e.g., clopidogrel, antifungals)
• Not recommended for prolonged self-medication
• Seek medical advice if symptoms persist or worsen

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Pregel Tablet 40 mg (Pantoprazole Sodium) is a potent proton pump inhibitor used for the effective management of moderate to severe acid-related gastrointestinal disorders. It helps reduce stomach acid, relieve symptoms, and support healing when used under proper medical supervision.