Pregnyl Injection 5000 IU contains human chorionic gonadotrophin (hCG), a hormone used in the treatment of infertility in both men and women. It plays a key role in stimulating ovulation in women and increasing testosterone production in men. This injectable formulation is widely used in assisted reproductive therapies under medical supervision.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Human Chorionic Gonadotrophin (hCG) 5000 IU per vial
• Dosage Form: Powder for injection (reconstituted before use)

Mechanism of Action

hCG mimics the action of luteinizing hormone (LH). In females, it triggers final maturation and release of the egg (ovulation) from the ovary. In males, it stimulates Leydig cells in the testes to produce testosterone, supporting sperm production and fertility.

Indications

Pregnyl Injection 5000 IU is indicated for:

• Female infertility due to anovulation or ovulation disorders
• Assisted reproductive techniques (ART) such as IVF
• Male hypogonadism (low testosterone levels)
• Delayed puberty in selected cases
• Cryptorchidism (undescended testes) in boys (as prescribed)

Dosage and Administration

• Administered by intramuscular injection only under medical supervision
• Dosage depends on patient condition and treatment protocol
• Usually given as a single dose or repeated doses as prescribed
• Must be prepared using sterile diluent before injection
• Timing is critical in fertility treatment protocols

Benefits

• Stimulates ovulation in women undergoing fertility treatment
• Supports testosterone production in men
• Improves chances of conception in assisted reproduction
• Plays a key role in controlled ovarian stimulation protocols
• Useful in treating certain hormonal disorders

Possible Side Effects

Common side effects may include:

• Injection site pain or swelling
• Headache
• Fatigue
• Mood changes

Less common but serious side effects may include:

• Ovarian hyperstimulation syndrome (OHSS) in women
• Fluid retention
• Gynecomastia in men
• Allergic reactions (rare)

Precautions and Warnings

• Use only under specialist supervision (gynecologist/endocrinologist)
• Risk of multiple pregnancy in fertility treatments
• Monitor ovarian response during therapy
• Not recommended during unexplained vaginal bleeding
• Caution in patients with heart or kidney disorders

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store at 2°C–8°C (refrigerated)
• Do not freeze
• Protect from light
• Use reconstituted solution immediately as directed

Conclusion

Pregnyl Injection 5000 IU (Human Chorionic Gonadotrophin) is an important fertility hormone used in the treatment of infertility in both men and women. It supports ovulation and testosterone production and is a key component of assisted reproductive therapies when used under strict medical supervision.