A-Cold Syrup 4 mg/5 ml contains Bromhexine Hydrochloride, a mucolytic and expectorant agent used in the management of productive cough associated with respiratory tract disorders. It works by reducing the viscosity of thick mucus, making it easier to cough out and thereby improving airway clearance. A-Cold Syrup is suitable for both adults and children and is commonly prescribed in conditions involving excessive or sticky respiratory secretions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

A-Cold Syrup 4 mg/5 ml is indicated for the treatment of respiratory conditions associated with abnormal mucus secretion, including:

• Productive cough

• Acute and chronic bronchitis

• Tracheobronchitis

• Chronic obstructive pulmonary disease (COPD)

• Bronchial asthma with mucus plugging

• Upper and lower respiratory tract infections with thick sputum

By loosening mucus, the syrup helps relieve chest congestion and improves breathing comfort.

Therapeutic Class

Mucolytics and expectorants

Pharmacology

Bromhexine Hydrochloride is a synthetic derivative of the herbal compound vasicine. It acts by depolymerizing mucopolysaccharide fibers in mucus, resulting in reduced sputum viscosity. This facilitates expectoration and enhances mucociliary clearance from the respiratory tract.

Bromhexine also stimulates the production of serous secretions in the respiratory tract, which further dilutes thick mucus. Improved mucus clearance helps reduce coughing frequency and supports faster recovery from respiratory infections. After oral administration, bromhexine is well absorbed from the gastrointestinal tract and distributed to lung tissue, where it exerts its therapeutic effect.

Mode of Action

A-Cold Syrup works by breaking down thick and sticky mucus in the airways, making it thinner and easier to expel. This action helps clear blocked airways, reduces chest congestion, and supports normal breathing.

Dosage and Administration

Dosage depends on age and severity of symptoms:

• Adults: 5–10 ml, two to three times daily

• Children: Dose adjusted according to age and body weight, as prescribed by a physician

The syrup should be taken after meals with adequate fluid intake to enhance the mucolytic effect.

Drug Interactions

Bromhexine may increase the penetration of certain antibiotics such as amoxicillin, erythromycin, and doxycycline into bronchial secretions, which may enhance their therapeutic effect. No significant adverse drug interactions have been commonly reported.

Contraindications

A-Cold Syrup is contraindicated in patients with:

• Known hypersensitivity to bromhexine or any component of the formulation

• Active peptic ulcer disease

Caution is advised in patients with severe hepatic or renal impairment.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

A-Cold Syrup is generally well tolerated. Some patients may experience:

• Mild gastrointestinal discomfort

• Nausea or vomiting

• Headache

• Skin rash (rare)

These side effects are usually mild and resolve with continued use.

Pregnancy and Lactation

The use of A-Cold Syrup during pregnancy and lactation should be based on a physician’s advice. It is generally used with caution, especially during the first trimester.

Storage Conditions

Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.