A-Fenac K Tablet 50 mg contains Diclofenac Potassium, a fast-acting nonsteroidal anti-inflammatory drug (NSAID) widely used for the management of acute pain and inflammatory conditions. Compared to diclofenac sodium, the potassium salt is absorbed more rapidly, providing quicker onset of analgesic action. This makes A-Fenac K particularly suitable for conditions where prompt pain relief is required.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

A-Fenac K Tablet 50 mg is indicated for the short-term treatment of mild to moderate pain and inflammation, including:

• Acute musculoskeletal pain

• Backache and neck pain

• Dental pain and post-dental procedure pain

• Headache and migraine attacks

• Post-operative and post-traumatic pain

• Painful inflammatory conditions of joints and soft tissues

• Dysmenorrhea

It is intended for use in adults and adolescents as prescribed by a healthcare professional.

Therapeutic Class

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

Pharmacology

Diclofenac Potassium works by inhibiting cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the formation of prostaglandins. Prostaglandins play a central role in the development of pain, inflammation, and fever. By suppressing prostaglandin synthesis, diclofenac effectively reduces these symptoms.

After oral administration, diclofenac potassium is rapidly absorbed from the gastrointestinal tract, leading to faster peak plasma concentrations compared to diclofenac sodium. The drug is highly bound to plasma proteins and undergoes extensive hepatic metabolism. Its metabolites are excreted primarily via the kidneys, with a small amount eliminated through bile. The relatively short plasma half-life supports flexible dosing for acute pain management.

Mechanism of Action

A-Fenac K Tablet provides analgesic, anti-inflammatory, and antipyretic effects by blocking prostaglandin production at the site of tissue injury. This results in rapid relief of pain, reduction of swelling, and improvement in functional mobility.

Dosage and Administration

• Adults: 50 mg up to two or three times daily, depending on severity of symptoms

• Adolescents: Dosage should be adjusted based on body weight and clinical condition

Tablets should be taken with or after food to reduce gastrointestinal discomfort. The lowest effective dose should be used for the shortest duration necessary.

Drug Interactions

Diclofenac may interact with other NSAIDs, corticosteroids, anticoagulants, antiplatelet agents, antihypertensive drugs, diuretics, lithium, and methotrexate. Such interactions may increase the risk of gastrointestinal bleeding, renal impairment, or reduced antihypertensive efficacy.

Contraindications

A-Fenac K Tablet 50 mg is contraindicated in patients with:

• Hypersensitivity to diclofenac or other NSAIDs

• History of NSAID-induced asthma, urticaria, or allergic reactions

• Active or recurrent peptic ulcer disease

• Severe hepatic, renal, or cardiac impairment

Side Effects

Possible side effects include:

• Gastrointestinal discomfort, nausea, or dyspepsia

• Headache or dizziness

• Skin rash

Serious adverse effects such as gastrointestinal bleeding or cardiovascular events are rare when used at recommended doses for short periods.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Pregnancy and Lactation

Diclofenac is contraindicated during the third trimester of pregnancy and should be used cautiously during earlier stages only if clearly necessary. Use during breastfeeding should be under medical supervision.

Storage Conditions

Store below 30°C in a cool and dry place. Protect from moisture and light. Keep out of reach of children.