A-Flox Capsule 500 mg contains Flucloxacillin Sodium, a penicillinase-resistant, narrow-spectrum antibiotic from the beta-lactam penicillin group. It is specifically designed to treat infections caused by penicillin-resistant Gram-positive bacteria, particularly Staphylococcus aureus. This higher-strength formulation is commonly prescribed for moderate to severe infections where a stronger antibacterial effect is required.

Flucloxacillin is well known for its targeted action, clinical reliability, and long-standing use in the management of staphylococcal infections. A-Flox Capsule 500 mg provides effective bacterial eradication when taken as directed, helping to reduce symptoms, control infection, and prevent complications.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Flucloxacillin Sodium BP equivalent to Flucloxacillin 500 mg

Therapeutic Class

• Beta-lactam antibiotic

• Penicillinase-resistant penicillin

Indications

A-Flox Capsule 500 mg is indicated for the treatment of a wide range of bacterial infections caused by susceptible organisms, including:

Skin and Soft Tissue Infections

• Cellulitis

• Infected wounds

• Abscesses

• Boils and carbuncles

• Infected burns

Bone and Joint Infections

• Osteomyelitis

• Septic arthritis

Respiratory Tract Infections

• Pneumonia

• Bronchitis

• Tonsillitis

• Pharyngitis

Ear, Nose, and Throat Infections

• Otitis media

• Sinusitis

Other Uses

• Prophylaxis against staphylococcal infection in certain surgical procedures, as advised by a healthcare professional

Mechanism of Action

Flucloxacillin exerts its antibacterial effect by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins within the bacterial cell wall, disrupting the formation of peptidoglycan, an essential structural component. This leads to weakening of the cell wall and eventual bacterial cell death.

A key advantage of Flucloxacillin is its resistance to beta-lactamase enzymes produced by many staphylococcal strains. This allows A-Flox Capsule 500 mg to remain effective against penicillin-resistant Staphylococcus aureus, making it a preferred choice in suspected or confirmed staphylococcal infections.

Dosage and Administration

A-Flox Capsule 500 mg should be taken orally as prescribed by a physician. For optimal absorption, it is generally recommended to take the capsule on an empty stomach, approximately one hour before meals or two hours after meals.

The dosage, frequency, and duration of treatment depend on the type and severity of infection, as well as patient-specific factors such as age, body weight, and renal function. Patients should complete the full course of therapy even if symptoms improve earlier.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Contraindicated in patients with known hypersensitivity to penicillins or other beta-lactam antibiotics.

• Use with caution in patients with hepatic impairment, as rare cases of cholestatic hepatitis have been reported.

• Long-term use may result in overgrowth of non-susceptible organisms.

Possible Side Effects

Common side effects include:

• Nausea

• Diarrhea

• Mild gastrointestinal discomfort

• Skin rash

Rare but serious reactions such as allergic responses or liver function abnormalities require immediate medical attention.

Storage Conditions

Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.