A-Migel Oral Gel 2% w/w contains Miconazole Nitrate, a broad-spectrum antifungal agent used for the treatment of fungal infections of the mouth and throat. It is especially effective against Candida species, which are the most common cause of oral candidiasis (oral thrush). The gel formulation is designed to adhere well to the oral mucosa, allowing prolonged contact with the affected area and ensuring effective antifungal action.

A-Migel Oral Gel is suitable for use in adults, children, and infants (as advised by a healthcare professional). Its pleasant gel base makes it easy to apply and swallow, improving patient compliance during antifungal therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each gram of oral gel contains:

• Miconazole Nitrate BP 20 mg
  (Equivalent to 2% w/w)

Therapeutic Class

• Antifungal

• Imidazole derivative

Indications

A-Migel Oral Gel 2% w/w is indicated for the treatment of fungal infections of the oral cavity and upper gastrointestinal tract, including:

Oral Candidiasis (Oral Thrush)

• White patches in the mouth or on the tongue

• Redness, soreness, and discomfort

• Difficulty in eating or swallowing due to fungal infection

Angular Stomatitis

• Fungal infection at the corners of the mouth

Denture-Related Oral Infections

• Candida-associated infections under dentures

Oropharyngeal and Gastrointestinal Candidiasis

• Helps prevent fungal overgrowth spreading from the mouth to the throat or upper digestive tract

The use of A-Migel Oral Gel should be based on clinical diagnosis and medical advice.

Mechanism of Action

Miconazole Nitrate works by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes. By disrupting ergosterol production, the integrity of the fungal cell membrane is compromised, leading to leakage of cellular contents and eventual cell death.

In addition to its antifungal activity, Miconazole also exhibits mild antibacterial effects against certain Gram-positive bacteria, which can be beneficial in mixed infections commonly seen in oral conditions.

The gel formulation ensures that the medication remains in contact with the affected areas for an extended period, enhancing its therapeutic effectiveness.

Dosage and Administration

A-Migel Oral Gel 2% w/w should be used exactly as prescribed by a healthcare professional. The gel is usually applied directly to the affected areas of the mouth using a clean finger or applicator.

It is recommended to keep the gel in the mouth for as long as possible before swallowing to allow maximum contact with the infected tissues. Treatment should be continued for the full prescribed duration, even if symptoms improve earlier, to prevent recurrence of infection.

For infants and young children, the gel should be applied carefully in small amounts to avoid the risk of choking.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Not recommended for patients with known hypersensitivity to miconazole or other imidazole antifungals.

• Use with caution in patients taking anticoagulant medicines, as miconazole may enhance their effects.

• Prolonged use without medical supervision is not advised.

Possible Side Effects

Most patients tolerate A-Migel Oral Gel well. Mild side effects may include:

• Temporary irritation or burning sensation in the mouth

• Nausea or unpleasant taste

Rare allergic reactions may occur. Discontinue use and seek medical advice if severe irritation or hypersensitivity develops.

Storage Conditions

Store in a cool, dry place below 25°C. Protect from direct sunlight. Keep out of reach of children.