Abecab Tablet 5 mg+40 mg is a combination antihypertensive medication formulated with Amlodipine Besilate and Olmesartan Medoxomil. This dual therapy is designed to provide effective and sustained control of high blood pressure by targeting two different physiological pathways. Amlodipine, a calcium channel blocker, helps relax blood vessels, while Olmesartan, an angiotensin II receptor blocker (ARB), prevents blood vessel constriction. Together, they improve blood flow and reduce cardiovascular risk.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Abecab Tablet is indicated for:

• Treatment of hypertension (high blood pressure)
• Patients requiring combination therapy for better blood pressure control
• Reduction of cardiovascular risks such as stroke, heart attack, and kidney complications

This combination is particularly useful in patients whose blood pressure is not adequately controlled with a single medication.

Mechanism of Action

• Amlodipine Besilate blocks calcium entry into vascular smooth muscle cells, leading to vasodilation and reduced peripheral resistance.
• Olmesartan Medoxomil inhibits the action of angiotensin II by blocking its receptors, thereby preventing vasoconstriction and lowering blood pressure.

The combination offers a complementary effect, resulting in improved blood pressure control.

Dosage and Administration

• The usual recommended dose is one tablet once daily or as directed by a physician.
• It can be taken with or without food.
• Swallow the tablet whole with a glass of water.
• Take the medicine at the same time each day to maintain consistent blood levels.

Dose adjustments may be required depending on patient response and clinical condition.

Side Effects

Common side effects may include:

• Dizziness
• Headache
• Peripheral edema (swelling of ankles or feet)
• Fatigue

Less common but serious side effects include:

• Severe hypotension
• Kidney function changes
• Elevated potassium levels (hyperkalemia)
• Allergic reactions

Seek immediate medical attention if serious side effects occur.

Precautions and Warnings

• Regular monitoring of blood pressure is important during treatment.
• Use cautiously in patients with kidney or liver impairment.
• Avoid use during pregnancy due to potential risk to the fetus.
• Do not use potassium supplements or potassium-containing salt substitutes without medical advice.
• Inform your doctor about any underlying medical conditions or ongoing treatments.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Abecab Tablet may interact with:

• Other antihypertensive drugs (additive blood pressure-lowering effect)
• Potassium-sparing diuretics or supplements
• NSAIDs (may reduce effectiveness)
• Lithium (increased risk of toxicity)

Always inform your healthcare provider about all medicines you are taking.

Storage Instructions

• Store below 25°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.