Acilog SC Injection 100 IU/ml contains Insulin Aspart [Protamine Crystallised], a rapid-acting insulin analogue formulated for subcutaneous administration to manage blood glucose levels in patients with diabetes mellitus. This insulin preparation provides both immediate and intermediate glycemic control due to its combination of soluble insulin aspart and protamine-crystallized insulin aspart. It is designed to mimic physiological insulin secretion, helping patients maintain stable blood sugar levels throughout the day, particularly around meals.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Acilog SC Injection 100 IU/ml is indicated for:

• Management of type 1 diabetes mellitus in adults and children
• Management of type 2 diabetes mellitus when diet, exercise, and oral antidiabetic agents are insufficient
• Control of postprandial blood glucose levels in insulin-requiring patients
• Use in basal-bolus insulin therapy regimens

Mechanism of Action

• Insulin Aspart (Rapid-Acting Component): Quickly lowers blood glucose levels by promoting the uptake of glucose into muscle and fat tissues and inhibiting hepatic glucose production. This component acts immediately after administration, controlling postprandial glucose spikes.
• Protamine-Crystallised Insulin Aspart (Intermediate-Acting Component): Provides a sustained insulin effect by slowing absorption, allowing for extended glycemic control and reducing the frequency of injections.

The combination ensures both rapid post-meal glucose regulation and prolonged basal coverage, offering effective glycemic management.

Dosage and Administration

• Administer subcutaneously using a syringe or insulin pen, typically 15–20 minutes before meals.
• Dosage is individualized based on blood glucose monitoring, dietary intake, and physician guidance.
• Rotate injection sites (abdomen, thigh, or upper arm) to prevent lipodystrophy.
• Do not inject intravenously or intramuscularly unless specified by a healthcare professional.
• Patients should monitor blood glucose regularly to adjust insulin dosage safely.

Side Effects

Common side effects may include:

• Hypoglycemia (low blood sugar) – sweating, dizziness, trembling
• Injection site reactions – redness, swelling, or itching
• Mild weight gain

Rare but serious side effects include:

• Severe hypoglycemia leading to unconsciousness or seizures
• Allergic reactions – rash, itching, or anaphylaxis
• Lipodystrophy at injection sites with repeated use

Immediate medical attention is required in case of severe hypoglycemia or allergic reactions.

Precautions and Warnings

• Monitor blood glucose frequently to prevent hypoglycemia or hyperglycemia.
• Use caution in patients with kidney or liver impairment.
• Inform your doctor if pregnant, breastfeeding, or planning pregnancy.
• Carry glucose or carbohydrate sources to manage hypoglycemic episodes.
• Avoid skipping meals after injection to prevent low blood sugar.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Acilog SC Injection may interact with:

• Oral antidiabetic drugs – may require dose adjustment
• Beta-blockers – may mask hypoglycemia symptoms
• Corticosteroids – may increase blood glucose levels
• Alcohol – may unpredictably affect glucose control

Inform your healthcare provider of all medications being taken.

Storage Instructions

• Store unopened vials or pens in a refrigerator at 2–8°C.
• Do not freeze.
• Protect from direct sunlight and heat.
• Once opened, keep at room temperature (below 30°C) and use within 28 days.
• Keep out of reach of children.