Adronic Injection 4 mg/5 ml contains Zoledronic Acid, a potent bisphosphonate used to treat hypercalcemia of malignancy (high blood calcium levels associated with cancer). It works by reducing the breakdown of bone, thereby lowering the release of calcium into the bloodstream and restoring normal calcium levels.

Hypercalcemia of malignancy is a serious medical condition that can occur in patients with certain cancers, such as breast cancer, lung cancer, multiple myeloma, and other malignancies involving the bones. Elevated calcium levels may cause symptoms such as excessive thirst, nausea, vomiting, constipation, fatigue, confusion, muscle weakness, and kidney problems. Adronic Injection helps rapidly lower blood calcium levels and reduces the risk of complications associated with severe hypercalcemia.

This medicine is administered by intravenous infusion under the supervision of a qualified healthcare professional in a hospital or clinical setting.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 5 ml vial contains:

• Zoledronic Acid 4 mg

Zoledronic Acid belongs to the bisphosphonate class of medicines.

Uses of Adronic Injection

Adronic Injection is used for the treatment of:

• Hypercalcemia of malignancy (high blood calcium caused by cancer)
• Elevated calcium levels associated with bone metastases
• Cancer-related bone complications (as prescribed by an oncologist)
• Other conditions requiring intravenous bisphosphonate therapy, as determined by a physician

How Adronic Injection Works

Zoledronic Acid works by inhibiting the activity of osteoclasts, the cells responsible for breaking down bone tissue. By slowing bone resorption, it reduces the release of calcium from bones into the bloodstream.

This helps normalize blood calcium levels, protects bone strength, and decreases the risk of skeletal complications in patients with cancer involving the bones.

Benefits of Adronic Injection

• Rapidly lowers elevated blood calcium levels
• Helps manage hypercalcemia associated with cancer
• Reduces excessive bone breakdown
• Protects bone health in patients with malignant bone disease
• Helps relieve symptoms caused by high calcium levels
• Lowers the risk of serious complications related to hypercalcemia

Dosage and Administration

Adronic Injection should be administered only by a qualified healthcare professional.

General instructions include:

• Administer as an intravenous infusion after appropriate dilution.
• Dosage is determined by the patient's medical condition, kidney function, and serum calcium levels.
• Adequate hydration should be ensured before and after treatment unless contraindicated.
• Regular monitoring of kidney function, serum calcium, phosphate, magnesium, and other electrolytes is recommended during therapy.

Possible Side Effects

Like all medicines, Adronic Injection may cause side effects, including:

• Fever
• Fatigue
• Headache
• Bone, joint, or muscle pain
• Nausea
• Vomiting
• Flu-like symptoms
• Low calcium levels (hypocalcemia)

Less common but serious side effects include:

• Kidney impairment
• Osteonecrosis of the jaw
• Severe allergic reactions
• Irregular heartbeat due to electrolyte disturbances

Seek immediate medical attention if severe symptoms develop.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

Before receiving Adronic Injection, inform your doctor if you have:

• Kidney disease
• Low blood calcium levels
• Vitamin D deficiency
• Dental problems or planned dental surgery
• Allergy to zoledronic acid or other bisphosphonates

Your doctor may recommend correcting low calcium or vitamin D levels before treatment. Good oral hygiene and routine dental check-ups are advised to reduce the risk of osteonecrosis of the jaw.

Adronic Injection is not recommended during pregnancy or breastfeeding unless clearly indicated by a healthcare professional.

Storage

• Store below 30°C.
• Protect from light.
• Keep the vial in its original packaging until use.
• Keep out of reach of children.