Afexa Tablet 180 mg contains Fexofenadine Hydrochloride 180 mg, a second-generation antihistamine used for the relief of allergy symptoms. It is commonly prescribed to manage conditions such as seasonal allergic rhinitis (hay fever) and chronic idiopathic urticaria (hives). Unlike first-generation antihistamines, Afexa is non-sedating, providing effective allergy relief without causing drowsiness, making it suitable for daytime use.

Fexofenadine works by selectively blocking histamine H1 receptors, preventing the action of histamine—a chemical mediator responsible for allergy symptoms such as itching, sneezing, runny nose, and skin rashes. Afexa 180 mg offers long-lasting relief, typically for 24 hours, allowing convenient once-daily dosing.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Fexofenadine Hydrochloride 180 mg

Mechanism of Action

Fexofenadine, the active ingredient in Afexa, is a selective H1 receptor antagonist. During an allergic reaction, the body releases histamine, which binds to H1 receptors and triggers common allergy symptoms:

• Nasal congestion

• Sneezing

• Itchy and watery eyes

• Skin rashes and hives

By blocking H1 receptors, Fexofenadine prevents histamine from exerting its effects, thereby reducing or eliminating these symptoms. Its non-sedating nature is due to its limited penetration across the blood-brain barrier, unlike older antihistamines that can cause drowsiness and impaired alertness.

Indications

Afexa Tablet 180 mg is indicated for the relief of:

• Seasonal allergic rhinitis: including sneezing, runny nose, itchy or watery eyes, and nasal congestion caused by pollen, dust, or other allergens

• Chronic idiopathic urticaria (hives): reducing itching, redness, and swelling of the skin

Benefits

• Non-Drowsy Relief: Suitable for daytime use without impairing alertness or concentration

• Once-Daily Dosing: Convenient and improves patient adherence

• Effective Symptom Control: Alleviates sneezing, itching, runny nose, and hives

• Rapid Onset of Action: Provides relief within 1–2 hours after intake

• Safe for Long-Term Use: Can be used for ongoing seasonal allergies or chronic hives under medical supervision

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Dosage and Administration

The recommended dose for adults and children over 12 years is 180 mg once daily, preferably with water. Afexa can be taken with or without food, but should not be taken with fruit juices like grapefruit, orange, or apple juice, as they may reduce the absorption and effectiveness of the medicine.

The dosage may be adjusted by a healthcare professional based on individual response, severity of symptoms, and any coexisting medical conditions.

Safety and Precautions

• Generally well-tolerated with minimal side effects

• Possible mild side effects include headache, dizziness, nausea, or dry mouth

• Not recommended for patients with known hypersensitivity to fexofenadine or other antihistamines

• Use caution in patients with kidney or liver impairment

• Not intended for the treatment of acute severe allergic reactions (anaphylaxis); epinephrine should be used in such cases

• Always inform your healthcare provider about other medications and medical conditions before starting therapy.