Amovast Tablet is a combination medicine containing Amlodipine Besilate and Atorvastatin. It is used for the management of high blood pressure (hypertension) along with elevated cholesterol levels. This dual-action therapy helps control blood pressure while also reducing harmful cholesterol and triglyceride levels, thereby lowering the risk of heart attack, stroke, and other cardiovascular complications.

Amlodipine relaxes blood vessels to improve blood flow, while Atorvastatin reduces cholesterol production in the liver.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Amovast Tablet is indicated for:

• Hypertension (high blood pressure)
• Hypercholesterolemia (high cholesterol levels)
• Mixed dyslipidemia
• Prevention of cardiovascular diseases such as heart attack and stroke
• Patients requiring combined BP and lipid control therapy

Mechanism of Action

• Amlodipine Besilate: A calcium channel blocker that relaxes vascular smooth muscles, leading to vasodilation and reduced blood pressure.
• Atorvastatin: A HMG-CoA reductase inhibitor (statin) that reduces cholesterol synthesis in the liver, lowering LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol).

Together, they improve cardiovascular health and reduce arterial plaque formation.

Dosage and Administration

• Dosage should be prescribed by a physician based on patient condition
• Usually taken once daily
• Can be taken with or without food
• Swallow the tablet whole with water
• Regular use is important for long-term cardiovascular protection

Side Effects

Common side effects may include:

• Headache
• Muscle pain or weakness
• Dizziness
• Swelling of ankles (edema)
• Nausea

Serious side effects may include:

• Liver function abnormalities
• Severe muscle breakdown (rare rhabdomyolysis)
• Significant drop in blood pressure
• Allergic reactions

Seek medical attention if severe symptoms occur.

Precautions and Warnings

• Regular monitoring of liver function tests is recommended
• Use cautiously in patients with liver or kidney disease
• Avoid excessive alcohol consumption
• Not recommended during pregnancy or breastfeeding
• Grapefruit juice should be avoided due to interaction with Atorvastatin
• Do not stop medication without medical advice

Drug Interactions

Amovast Tablet may interact with:

• Other cholesterol-lowering medicines
• Strong CYP3A4 inhibitors (certain antibiotics and antifungals)
• Blood pressure medications
• Anticoagulants (warfarin)
• Alcohol (increased liver risk)

Always inform your healthcare provider about all medicines you are taking.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children

Conclusion

Amovast Tablet 5 mg + 10 mg (Amlodipine Besilate + Atorvastatin) is an effective combination therapy for managing hypertension and high cholesterol. It provides comprehensive cardiovascular protection by controlling blood pressure and lipid levels, helping reduce the risk of heart disease and stroke when used under medical supervision.