Anaflex SR Tablet 500 mg contains Naproxen Sodium, a non-steroidal anti-inflammatory drug (NSAID) formulated in a sustained-release (SR) form. This allows for prolonged therapeutic action, providing long-lasting relief from pain, inflammation, and stiffness associated with musculoskeletal and inflammatory conditions. The sustained-release formulation helps maintain consistent drug levels in the blood, reducing the frequency of dosing and improving patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Naproxen Sodium 500 mg (sustained-release)

Mechanism of Action

Naproxen Sodium inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins, which are responsible for pain, inflammation, and swelling. The sustained-release formulation ensures gradual absorption over time, maintaining prolonged anti-inflammatory and analgesic effects.

Indications

Anaflex SR Tablet 500 mg is indicated for:

• Osteoarthritis and rheumatoid arthritis
• Ankylosing spondylitis
• Chronic musculoskeletal pain
• Soft tissue injuries such as sprains and strains
• Gout attacks
• Inflammatory conditions requiring long-acting NSAID therapy

Dosage and Administration

• Adults: Typically one tablet once daily or as directed by a physician.
• Swallow the tablet whole with a full glass of water, preferably after meals to minimize gastrointestinal irritation.
• Do not crush, chew, or break the tablet, as this will compromise the sustained-release mechanism.
• Dosage may be adjusted based on the severity of symptoms and patient tolerance.

Benefits

• Provides long-lasting relief from pain and inflammation
• Reduces joint stiffness and improves mobility
• Sustained-release formulation allows convenient once-daily dosing
• Suitable for chronic conditions requiring consistent anti-inflammatory action
• Minimizes peak-trough fluctuations in drug levels for better tolerability

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, or heartburn
• Abdominal discomfort or bloating
• Headache or dizziness
• Mild swelling or fluid retention

Rare but serious side effects:

• Gastrointestinal bleeding or ulcers
• Liver or kidney function disturbances
• Allergic reactions such as rash or swelling
• Severe cardiovascular events (in patients with risk factors)

Precautions and Warnings

• Take with food or milk to reduce stomach irritation.
• Use with caution in patients with a history of gastrointestinal ulcers, bleeding disorders, heart, kidney, or liver disease.
• Avoid during the third trimester of pregnancy unless prescribed by a physician.
• Consult a doctor before use during breastfeeding.
• Avoid concurrent use of other NSAIDs unless advised by a healthcare provider.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Anaflex SR Tablet may interact with:

• Anticoagulants (e.g., warfarin) – increased risk of bleeding
• Corticosteroids – higher risk of gastrointestinal irritation
• ACE inhibitors or diuretics – may affect kidney function
• Other NSAIDs – increased risk of adverse effects

Storage Instructions

• Store below 30°C in a cool, dry place
• Protect from light and moisture
• Keep out of reach of children.