Apuldon Pediatric Drop 5 mg/ml contains Domperidone Maleate, a medicine used to relieve nausea and vomiting and to improve stomach emptying in infants and children. It belongs to a group of medicines known as dopamine receptor antagonists (prokinetic agents). By enhancing the movement of the stomach and intestines, Apuldon Pediatric Drop helps food pass more easily through the digestive tract, reducing symptoms such as nausea, vomiting, bloating, and stomach discomfort.

Domperidone works by blocking dopamine receptors in the gastrointestinal tract and the brain's chemoreceptor trigger zone, which plays a role in triggering nausea and vomiting. Its prokinetic effect increases the contractions of the stomach and upper intestines, promoting faster gastric emptying without affecting normal digestive secretions. This makes it particularly useful in managing nausea and vomiting associated with gastrointestinal disorders or certain medications.

Apuldon Pediatric Drop is specially formulated for pediatric use, allowing accurate dose adjustment according to the child's age and body weight. It should always be administered under the guidance of a registered physician, and the recommended dose should not be exceeded.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each ml contains:

• Domperidone Maleate 5 mg

Indications

Apuldon Pediatric Drop is indicated for:

• Nausea and vomiting in infants and children
• Delayed gastric emptying (gastroparesis)
• Gastrointestinal discomfort associated with slow stomach motility
• Bloating and early fullness related to impaired gastric emptying
• Functional dyspepsia (as prescribed)

How It Works

Domperidone blocks dopamine receptors in the digestive system and the brain's vomiting center. This action reduces nausea and vomiting while enhancing stomach and intestinal movements, allowing food to move more efficiently through the gastrointestinal tract.

Dosage & Administration

• Use strictly as prescribed by a registered physician.
• The dose is based on the child's body weight and medical condition.
• Shake the bottle well before use.
• Measure the dose accurately using the supplied dropper or an oral dosing device.
• Administer the medicine 15–30 minutes before meals if advised by the physician.
• Do not exceed the recommended dose or duration of treatment.

Possible Side Effects

Some children may experience:

• Dry mouth
• Abdominal cramps
• Diarrhea
• Headache
• Drowsiness
• Irritability

Rare but serious side effects include allergic reactions, abnormal heart rhythm, or involuntary muscle movements. Seek immediate medical attention if these occur.

Precautions

• Use only under medical supervision in infants and children.
• Do not exceed the recommended dose, as higher doses may increase the risk of serious heart rhythm problems.
• Use cautiously in children with liver impairment or electrolyte imbalance.
• Inform your doctor if your child has any heart disease or is taking medicines that may affect heart rhythm.
• Discontinue the medicine and seek medical advice if severe allergic reactions or unusual symptoms develop.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Apuldon Pediatric Drop may interact with:

• Macrolide antibiotics (e.g., erythromycin, clarithromycin)
• Azole antifungal medicines (e.g., ketoconazole, itraconazole)
• Certain antiarrhythmic medicines
• Other medicines that prolong the QT interval
• Dopamine agonists

Always inform your healthcare provider about all medicines your child is taking before starting treatment.

Storage

• Store below 30°C.
• Protect from direct sunlight and moisture.
• Keep the bottle tightly closed.
• Keep out of reach of children.