Arthrofen Plus Injection (75 mg + 20 mg) / 2 ml is a combination injectable medication containing Diclofenac and Lidocaine. It is designed to provide rapid relief from moderate to severe pain and inflammation associated with musculoskeletal disorders, injuries, and postoperative conditions.

Pain and inflammation can significantly limit mobility and affect daily activities. Diclofenac Sodium works as a powerful nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation. Lidocaine Hydrochloride, a local anesthetic, is included in the formulation to reduce pain at the injection site and provide immediate local relief.

The combination of these two medicines makes Arthrofen Plus Injection particularly useful when quick pain control is required, such as in acute musculoskeletal conditions, trauma, or severe joint inflammation. It is commonly used in the treatment of conditions like Osteoarthritis, Rheumatoid Arthritis, and Ankylosing Spondylitis.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 2 ml ampoule contains:

• Diclofenac Sodium 75 mg

• Lidocaine Hydrochloride 20 mg

The injection is intended for intramuscular administration and should be given by a trained healthcare professional.

Mechanism of Action

Arthrofen Plus Injection works through the combined pharmacological actions of its two active ingredients.

Diclofenac Sodium acts by inhibiting cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins. Prostaglandins are chemical substances that play a major role in causing pain, swelling, and inflammation. By blocking their formation, Diclofenac effectively reduces inflammation and relieves pain.

Lidocaine Hydrochloride is a local anesthetic that works by blocking sodium channels in nerve cells. This prevents the transmission of pain signals from the injection site to the brain. As a result, it reduces discomfort during and shortly after the injection and provides additional pain relief.

The combination provides both anti-inflammatory effects and immediate local analgesia, making it effective for acute pain management.

Indications

Arthrofen Plus Injection is indicated for the short-term treatment of pain and inflammation in various conditions, including:

• Osteoarthritis

• Rheumatoid Arthritis

• Ankylosing Spondylitis

• Acute musculoskeletal pain

• Postoperative pain

• Traumatic injuries such as sprains or strains

• Severe back pain or joint pain

It is typically used when oral medications are not suitable or when rapid pain relief is required.

Dosage and Administration

Arthrofen Plus Injection should be administered only by a qualified healthcare professional. The dosage and frequency depend on the patient’s medical condition and response to treatment.

General administration guidelines include:

• Given by deep intramuscular injection, usually in the gluteal muscle.

• The injection should be administered slowly to minimize discomfort.

• Typically used for short-term treatment, after which patients may switch to oral medication if needed.

• Follow the doctor’s prescribed dosing schedule carefully.

Self-administration is not recommended.

Benefits

Arthrofen Plus Injection offers several important advantages:

• Provides rapid relief from moderate to severe pain

• Reduces inflammation and swelling in joints and muscles

• Improves mobility and physical comfort

• Contains lidocaine to reduce injection pain

• Suitable for acute pain management in clinical settings

These benefits make it a valuable option for short-term treatment of painful inflammatory conditions.

Possible Side Effects

Some patients may experience side effects while receiving Arthrofen Plus Injection. Common side effects include:

• Pain or irritation at the injection site

• Nausea or vomiting

• Dizziness

• Headache

• Stomach discomfort

Serious side effects such as allergic reactions, gastrointestinal bleeding, or cardiovascular complications are rare but require immediate medical attention.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

Before using Arthrofen Plus Injection, patients should inform their healthcare provider if they have:

• A history of stomach ulcers or gastrointestinal bleeding

• Heart disease or high blood pressure

• Kidney or liver problems

• Allergy to NSAIDs or local anesthetics

This medication should not be used during pregnancy, especially in the later stages.

Patients should also avoid combining this injection with other NSAIDs unless advised by a doctor.

Storage

Store Arthrofen Plus Injection in a cool, dry place, away from direct light and excessive heat. Keep the ampoules in their original packaging and out of reach of children.