Belsar Plus Tablet 40 mg+12.5 mg is a combination antihypertensive medication containing Olmesartan Medoxomil and Hydrochlorothiazide. It is used for the treatment of high blood pressure (hypertension), especially in patients whose blood pressure is not adequately controlled with a single medication. This dual-action formula helps lower blood pressure more effectively and reduces the risk of serious cardiovascular complications such as heart attack, stroke, and kidney damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Olmesartan Medoxomil – 40 mg
• Hydrochlorothiazide – 12.5 mg

Mechanism of Action

This combination works through two complementary mechanisms:

• Olmesartan Medoxomil: An angiotensin II receptor blocker (ARB) that relaxes blood vessels by blocking the vasoconstrictor effects of angiotensin II, leading to reduced blood pressure
• Hydrochlorothiazide: A thiazide diuretic that helps eliminate excess salt and water from the body through urine, reducing blood volume and lowering blood pressure

Together, they provide enhanced blood pressure control compared to monotherapy.

Indications

Belsar Plus Tablet is indicated for:

• Treatment of essential hypertension
• Patients not adequately controlled on single-agent therapy
• Reduction of cardiovascular risks such as stroke and heart disease
• Support in preventing hypertension-related kidney damage

Dosage and Administration

• Recommended dose: one tablet once daily, or as prescribed by a physician
• Can be taken with or without food
• Take at the same time each day for optimal blood pressure control
• Dosage adjustments may be required based on patient response

Benefits

• Provides stronger blood pressure control with combination therapy
• Reduces risk of heart attack and stroke
• Helps eliminate excess fluid and salt from the body
• Improves overall cardiovascular health
• Convenient once-daily dosing

Possible Side Effects

Common side effects may include:

• Dizziness or lightheadedness
• Increased urination
• Fatigue
• Headache

Serious side effects (seek medical attention):

• Severe hypotension (low blood pressure)
• Electrolyte imbalance (low potassium or sodium)
• Kidney dysfunction
• Allergic reactions (rare)

Precautions and Warnings

• Contraindicated during pregnancy due to risk of fetal harm
• Use cautiously in patients with kidney or liver impairment
• Regular monitoring of blood pressure, kidney function, and electrolyte levels is recommended
• Avoid dehydration and excessive fluid loss
• Inform your doctor about all current medications and health conditions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

May interact with:

• Other antihypertensive agents
• Potassium supplements or potassium-sparing diuretics
• NSAIDs (may reduce effectiveness and affect kidney function)
• Lithium (risk of toxicity)
• Corticosteroids (may worsen electrolyte imbalance)

Storage

• Store below 30°C
• Keep in a dry place away from light
• Keep out of reach of children.