Bilovia Tablet 5 mg contains Obeticholic Acid, a potent farnesoid X receptor (FXR) agonist used for the treatment of chronic liver diseases. It is particularly effective in managing primary biliary cholangitis (PBC) in patients who have an inadequate response or intolerance to ursodeoxycholic acid (UDCA).

Obeticholic Acid works by regulating bile acid synthesis, reducing bile acid accumulation, and minimizing liver inflammation and fibrosis. Bilovia helps improve liver function, lowers liver enzyme levels, and slows the progression of liver damage.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Bilovia Tablet is indicated for:

• Primary biliary cholangitis (PBC) in adults, especially in patients with incomplete response or intolerance to ursodeoxycholic acid (UDCA)
• Reducing elevated liver enzymes associated with cholestatic liver diseases
• Slowing progression of liver fibrosis in chronic cholestatic conditions

Composition

• Active Ingredient: Obeticholic Acid
• Strength: 5 mg
• Dosage Form: Oral tablet

Mechanism of Action

Obeticholic Acid works as a farnesoid X receptor (FXR) agonist, providing the following actions:

• Regulates bile acid synthesis, reducing toxic bile accumulation in the liver
• Improves bile flow, preventing cholestasis
• Anti-inflammatory and antifibrotic effects, helping protect liver cells from further damage
• Modulates lipid and glucose metabolism, supporting overall liver health

This targeted mechanism makes it a key therapy for patients with progressive cholestatic liver diseases.

Dosage & Administration

• Adults: সাধারণত 5–10 mg once daily, orally, as directed by a physician
• Can be taken with or without food
• Start at the lower dose for patients with moderate to severe liver impairment and adjust based on response and tolerance
• Regular liver function tests should be conducted to monitor treatment response

Side Effects

Bilovia Tablet is generally well tolerated. Some potential side effects include:

• Pruritus (itching)
• Fatigue
• Abdominal discomfort
• Nausea
• Rare: elevated cholesterol or liver enzyme abnormalities

Patients should report persistent or severe symptoms to their healthcare provider.

Precautions & Warnings

• Monitor liver function regularly during therapy
• Use with caution in patients with decompensated liver disease
• Dose adjustment may be required in patients with severe hepatic impairment
• Not recommended for children or adolescents due to limited safety data
• Inform your physician of any concurrent medications, especially bile acid sequestrants or other liver therapies

Drug Interactions

• Bile acid sequestrants may reduce absorption of obeticholic acid; separate dosing by at least 4 hours
• Monitor co-administration with other hepatotoxic drugs

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Only if potential benefit justifies the risk
• Lactation: Avoid use; insufficient data
• Elderly: Use with caution; monitor liver function

Storage

• Store below 25°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.