Buviren Tablet 400 mg contains Sofosbuvir, a direct-acting antiviral (DAA) used for the treatment of chronic hepatitis C virus (HCV) infection. Sofosbuvir works by inhibiting the HCV NS5B polymerase, an enzyme essential for viral replication, thereby preventing the virus from multiplying in the liver.

Buviren is highly effective against multiple HCV genotypes and is commonly used as part of combination therapy with other antivirals such as ledipasvir, velpatasvir, or daclatasvir. The once-daily oral tablet formulation ensures convenient dosing and improved patient compliance.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Buviren Tablet 400 mg is indicated for:

• Chronic hepatitis C virus (HCV) infection in adults

• Combination therapy with other DAAs for optimal viral eradication

• Patients with or without compensated liver disease

Benefits of Buviren Tablet

• Highly effective antiviral that significantly reduces HCV viral load

• Supports sustained virologic response (SVR), often considered a functional cure

• Well-tolerated with fewer side effects compared to older interferon-based therapies

• Convenient once-daily oral dosing improves adherence

• Can be used in patients with mild to moderate liver impairment (as per physician guidance)

Dosage and Administration

• Typical dose: 400 mg orally once daily, with or without food

• Usually prescribed in combination with other DAAs according to genotype and patient condition

• Do not skip doses or discontinue therapy prematurely, as incomplete treatment may reduce efficacy

• Follow your healthcare provider’s instructions regarding duration of therapy, which typically ranges from 8 to 12 weeks

Precautions

Before taking Buviren Tablet, inform your doctor if you:

• Have severe liver or kidney impairment

• Are pregnant, planning pregnancy, or breastfeeding

• Are taking other medications, including over-the-counter drugs or herbal supplements, which may interact with Sofosbuvir

• Have a history of heart disease or other chronic illnesses

Patients should report any unusual symptoms such as severe fatigue, jaundice, or allergic reactions during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Fatigue or weakness

• Headache

• Nausea

• Insomnia

Rare but serious side effects:

• Severe allergic reactions (rash, swelling, difficulty breathing)

• Liver function abnormalities

• Cardiovascular events in predisposed patients (rare)

Storage Instructions

Store Buviren Tablet 400 mg in a cool, dry place, protected from light and moisture. Keep out of reach of children.