Caboz Capsule 20 mg contains Cabozantinib, a targeted anticancer medicine belonging to the class of tyrosine kinase inhibitors (TKIs). It is used in the treatment of various advanced cancers by blocking specific proteins that promote tumor growth and angiogenesis (formation of new blood vessels). Cabozantinib helps slow disease progression and improve survival outcomes in selected cancer patients.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Cabozantinib 20 mg
• Dosage Form: Oral capsule

Mechanism of Action

Cabozantinib inhibits multiple receptor tyrosine kinases, including VEGFR, MET, and AXL. These pathways are involved in tumor cell proliferation, metastasis, and blood vessel formation. By blocking these signals, Cabozantinib reduces tumor growth, limits metastasis, and decreases tumor blood supply, leading to cancer cell death or growth suppression.

Indications

Caboz Capsule 20 mg is indicated for:

• Advanced renal cell carcinoma (kidney cancer)
• Hepatocellular carcinoma (liver cancer)
• Medullary thyroid cancer
• Other solid tumors (as per oncologist recommendation)

Dosage and Administration

• Must be taken strictly under the supervision of an oncologist
• Dosage varies depending on indication and patient condition
• Usually taken once daily on an empty stomach
• Capsules should be swallowed whole with water (do not crush or chew)
• Treatment should follow a carefully monitored schedule

Precautions

• Not recommended during pregnancy or breastfeeding
• Regular monitoring of blood pressure and liver function is required
• May increase risk of bleeding or clotting disorders
• Use with caution in patients with heart disease or gastrointestinal issues
• Inform physician about all concurrent medications

Side Effects

Common side effects include:

• Fatigue and weakness
• Loss of appetite
• Diarrhea
• Nausea and vomiting
• Weight loss

Serious side effects:

• Hypertension (high blood pressure)
• Hemorrhage (bleeding)
• Gastrointestinal perforation
• Liver toxicity
• Palmar-plantar erythrodysesthesia (hand-foot syndrome)

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children
• Do not use after expiry date

Conclusion

Caboz Capsule 20 mg (Cabozantinib) is a targeted cancer therapy used in advanced solid tumors. It works by blocking key pathways involved in tumor growth and angiogenesis. Due to its potent effects and potential risks, it should only be used under strict medical supervision.