D-gest Tablet 10 mg contains Dydrogesterone, a synthetic hormone structurally similar to natural progesterone. It is widely used in the management of gynecological and reproductive health conditions where progesterone deficiency is implicated. Dydrogesterone works by supporting hormonal balance, regulating the menstrual cycle, and maintaining a suitable endometrial environment for pregnancy. Its targeted action provides effective relief from menstrual disorders, luteal phase defects, and other progesterone-related conditions while maintaining a favorable safety profile.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Dydrogesterone 10 mg

• Dosage Form: Oral tablet

• Route of Administration: Oral

Mechanism of Action

Dydrogesterone is a selective progestogen that binds to progesterone receptors in target tissues. Its actions include:

• Supporting endometrial development and secretory transformation

• Regulating menstrual cycles by mimicking natural progesterone activity

• Maintaining pregnancy by preparing the endometrium for implantation

• Reducing excessive endometrial proliferation in estrogen-dominant states

• Modulating hormonal balance in conditions associated with progesterone deficiency

This selective mechanism ensures that Dydrogesterone provides therapeutic benefits without the androgenic, estrogenic, or glucocorticoid effects often associated with other synthetic progestins.

Indications

D-gest Tablet 10 mg is indicated for:

• Menstrual disorders such as irregular cycles, dysmenorrhea, or premenstrual syndrome (PMS)

• Luteal phase deficiency, which may contribute to infertility or early miscarriage

• Threatened or habitual miscarriage to support pregnancy maintenance

• Endometriosis to relieve symptoms and prevent endometrial overgrowth

• Hormone replacement therapy in combination with estrogen for postmenopausal women to prevent endometrial hyperplasia

• Other gynecological conditions associated with progesterone insufficiency

Dosage and Administration

• Adults: Typically 10–20 mg daily for 5–10 days per menstrual cycle, depending on the condition and physician’s guidance

• Can be administered continuously or cyclically as advised by a healthcare professional

• Swallow the tablet with water, with or after food for better tolerance

• Dosage and duration should be individualized based on patient needs and clinical response

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Contraindications

D-gest Tablet is contraindicated in:

• Patients with hypersensitivity to dydrogesterone or any component of the tablet

• Active thrombophlebitis, thromboembolic disorders, or history of deep vein thrombosis

• Undiagnosed vaginal bleeding

• Severe liver dysfunction

Precautions and Warnings

• Monitor in patients with a history of thromboembolic disorders, diabetes, or hypertension

• Not recommended during the first trimester unless specifically indicated for miscarriage prevention

• Use caution in patients with hormone-sensitive cancers

• Inform your doctor of all current medications to avoid potential interactions

Possible Side Effects

D-gest Tablet is generally well tolerated. Some mild side effects may include:

• Nausea or abdominal discomfort

• Breast tenderness

• Headache or mild dizziness

• Rare effects: allergic reactions, mood changes, or fluid retention

Storage

Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Conclusion

D-gest Tablet 10 mg provides effective hormone support for women with progesterone deficiency, menstrual disorders, luteal phase defects, or risk of miscarriage. Its selective action, safety, and ease of use make it a reliable option for promoting reproductive and gynecological health under medical supervision.