Daclavir Tablet 60 mg contains Daclatasvir, an antiviral medication used in the treatment of chronic Hepatitis C virus (HCV) infection. It is a direct-acting antiviral (DAA) that works by inhibiting viral replication, helping to clear the infection from the body. Daclavir is typically used in combination with other antiviral agents such as Sofosbuvir for improved treatment outcomes.

This medicine is not effective as monotherapy and should always be used as part of a combination regimen prescribed by a healthcare professional.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each film-coated tablet contains:

• Daclatasvir 60 mg

Mechanism of Action

Daclatasvir is an inhibitor of the HCV NS5A protein, which is essential for viral replication and assembly. By blocking this protein, Daclavir disrupts multiple stages of the Hepatitis C virus life cycle, leading to reduced viral load and eventual clearance of infection when used in combination therapy.

Indications

Daclavir Tablet 60 mg is indicated for:

• Chronic Hepatitis C virus (HCV) infection
• HCV genotype 1, 2, 3, and 4 (depending on combination regimen)
• Patients with or without compensated liver disease (as prescribed)
• Combination therapy with Sofosbuvir and other antiviral agents

Dosage and Administration

• Should be taken orally once daily as prescribed by a physician
• Can be taken with or without food
• Must be used in combination with other antiviral medications (not as monotherapy)
• Treatment duration typically ranges from 12 to 24 weeks depending on genotype and patient condition
• Strict adherence to prescribed regimen is essential for effective viral suppression

Contraindications

Daclavir Tablet should not be used in:

• Known hypersensitivity to Daclatasvir or any excipients
• Use as monotherapy in Hepatitis C treatment
• Severe drug interactions without physician approval
• Pregnancy unless clearly recommended by a specialist

Side Effects

Common side effects may include:

• Headache
• Fatigue
• Nausea
• Diarrhea
• Insomnia
• Mild anemia (when used with other antivirals)

Rare but serious effects depend on combination therapy and underlying liver condition.

Precautions

• Always use in combination therapy as directed
• Liver function should be monitored during treatment
• Caution in patients with advanced liver disease
• Avoid skipping doses to prevent treatment failure or resistance
• Drug interactions should be carefully evaluated before starting therapy

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Daclavir Tablet may interact with:

• Strong CYP3A inducers (e.g., rifampicin, phenytoin) reducing effectiveness
• Certain antiepileptics and antibiotics
• HIV medications (dose adjustment may be required)
• Other antivirals used in HCV treatment

Storage Conditions

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.