Dentro Capsule 25 mg contains Dantrolene Sodium. It is primarily used to relieve muscle stiffness and spasms associated with neurological disorders, and it also plays a crucial role in the treatment and prevention of malignant hyperthermia, a serious reaction to certain anesthetic agents.

This lower-strength formulation is often used at the start of therapy or in patients who require gradual dose adjustment to minimize side effects.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each capsule contains:

• Dantrolene Sodium 25 mg

It is intended for oral use.

Mechanism of Action

Dantrolene acts directly on skeletal muscle:

• Inhibits the release of calcium ions from the sarcoplasmic reticulum
• Reduces muscle contraction strength
• Decreases muscle rigidity and spasms
• Helps restore more normal muscle tone

Unlike centrally acting muscle relaxants, it does not significantly depress the central nervous system.

Indications

Dentro Capsule 25 mg is indicated for:

• Spasticity
• Cerebral Palsy
• Spinal Cord Injury
• Malignant Hyperthermia

Dosage and Administration

• Initial dosing is usually low (such as 25 mg once daily) and gradually increased
• Taken 1–3 times daily, depending on response
• May be taken with or without food
• Dosage should be adjusted carefully under medical supervision

Benefits

Dentro Capsule 25 mg offers several benefits:

• Relieves muscle stiffness and spasms
• Improves movement and flexibility
• Helps patients with neurological disorders perform daily activities
• Allows gradual dose titration to minimize side effects
• Essential in preventing and treating malignant hyperthermia

Possible Side Effects

Common side effects include:

• Drowsiness
• Dizziness
• Weakness
• Diarrhea

Serious side effects may include:

• Liver damage (hepatotoxicity)
• Severe muscle weakness
• Breathing difficulties (rare)
• Allergic reactions

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions

• Regular liver function tests are recommended during long-term use
• Use cautiously in patients with liver disease
• Avoid driving or operating machinery if drowsy
• Use with caution in elderly patients
• Inform your doctor about all other medications

Storage

Store in a cool, dry place below 30°C, away from light and moisture. Keep out of reach of children.