Diampa M Tablet 5 mg + 500 mg is a combination oral antidiabetic medication containing Empagliflozin 5 mg and Metformin Hydrochloride 500 mg. This dual-action formulation is designed for the management of type 2 diabetes mellitus in adults, particularly for patients whose blood sugar levels are not adequately controlled by diet, exercise, or monotherapy.

Empagliflozin, a SGLT2 inhibitor, promotes glucose excretion through the urine, while Metformin reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues. Together, they provide complementary mechanisms to effectively lower blood sugar levels, manage weight, and improve overall metabolic health.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Empagliflozin 5 mg

• Metformin Hydrochloride 500 mg

Mechanism of Action

The combination works through two distinct mechanisms:

1. Empagliflozin:

   • Inhibits sodium-glucose co-transporter 2 (SGLT2) in the kidneys

   • Increases urinary glucose excretion, lowering blood sugar independently of insulin

   • Helps reduce body weight and may lower blood pressure slightly

2. Metformin Hydrochloride:

   • Reduces hepatic glucose production

   • Enhances insulin sensitivity in muscles and fat tissue

   • Improves peripheral glucose uptake and utilization

By combining these effects, Diampa M achieves better glycemic control than either drug alone, with a lower risk of hypoglycemia when used as prescribed.

Indications

Diampa M Tablet 5 mg + 500 mg is indicated for:

• Adults with type 2 diabetes mellitus requiring dual therapy

• Patients whose blood sugar is inadequately controlled with lifestyle modifications or monotherapy

• Supportive therapy to manage weight and reduce cardiovascular risk in type 2 diabetes patients

• Adjunctive treatment for improving overall metabolic parameters

Dosage and Administration

• The usual dose is one tablet orally once or twice daily, taken with meals to reduce gastrointestinal discomfort.

• Adjustments may be made based on kidney function, blood sugar levels, and clinical response under medical supervision.

• Maintain a healthy diet and regular exercise regimen while on therapy.

• Regular monitoring of blood glucose, kidney function, and overall metabolic status is recommended.

Precautions

• Not recommended in patients with severe kidney impairment, liver disease, or metabolic acidosis.

• Use with caution in patients prone to dehydration or hypotension.

• May increase the risk of urinary tract infections or genital infections due to Empagliflozin.

• Inform your healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid interactions.

• Pregnancy and breastfeeding: only use under medical supervision.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Nausea, vomiting, or diarrhea (mostly due to Metformin)

• Increased urination or mild dehydration (Empagliflozin effect)

• Genital yeast infections

• Mild dizziness or fatigue

Serious but rare side effects include lactic acidosis, severe kidney problems, or diabetic ketoacidosis. Immediate medical attention is required if severe symptoms occur.

Storage

• Store below 25°C in a cool, dry place

• Protect from light and moisture

• Keep out of reach of children

Diampa M Tablet 5 mg + 500 mg is a safe and effective combination therapy for type 2 diabetes. Its dual mechanism provides enhanced blood sugar control, weight management, and cardiovascular support, making it an ideal choice for patients requiring comprehensive glycemic management.