Dicephin Injection 500 mg/vial contains Ceftriaxone Sodium 500 mg, a third-generation cephalosporin antibiotic widely used to treat a broad spectrum of bacterial infections. Ceftriaxone is highly effective against both gram-positive and gram-negative bacteria and works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Dicephin Injection 500 mg is formulated for intravenous (IV) or intramuscular (IM) administration, making it suitable for moderate to severe infections where rapid and reliable antibacterial action is required.

The long half-life of Ceftriaxone allows for once or twice-daily dosing, improving compliance and providing sustained therapeutic levels. Dicephin Injection is commonly used in hospital and outpatient settings for patients requiring prompt and effective management of bacterial infections, including those caused by resistant strains.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Dicephin Injection 500 mg/vial is indicated for the treatment of infections caused by susceptible bacteria, including:

• Respiratory tract infections: pneumonia, acute bronchitis, and lower respiratory infections

• Ear, nose, and throat infections: otitis media, sinusitis, tonsillitis, and pharyngitis

• Skin and soft tissue infections: cellulitis, abscesses, wound infections, and burns

• Urinary tract infections: cystitis, pyelonephritis, and complicated urinary infections

• Bone and joint infections such as osteomyelitis under medical supervision

• Septicemia and bacteremia caused by susceptible organisms

• Gonococcal infections and other sexually transmitted infections caused by sensitive strains

• Surgical prophylaxis in high-risk procedures to prevent postoperative infections

Dicephin Injection should be used only for confirmed or strongly suspected bacterial infections to prevent the development of antibiotic resistance.

Dosage and Administration

The dosage of Dicephin Injection 500 mg/vial should be individualized by a healthcare professional based on infection type, severity, patient age, weight, and renal function:

• Adults: Typically 500 mg to 2 g daily, either as a single dose or divided into one or two doses; severe infections may require higher doses

• Children: 50–75 mg/kg/day divided into one or two doses, depending on infection severity

• Reconstitute the vial with a suitable diluent according to manufacturer instructions

• Administer via intravenous infusion or intramuscular injection; slow IV injection is recommended

• Complete the full prescribed course even if symptoms improve early to prevent recurrence and antibiotic resistance

Precautions

• Contraindicated in patients with known hypersensitivity to cephalosporins or penicillin

• Use cautiously in patients with renal or hepatic impairment; dose adjustments may be necessary

• Avoid mixing with calcium-containing solutions in neonates due to risk of precipitation

• Monitor for superinfections during prolonged therapy

• Inform the physician about all medications being taken to avoid potential drug interactions

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Dicephin Injection 500 mg/vial is generally well tolerated. Common side effects include:

• Pain, redness, or swelling at the injection site

• Gastrointestinal disturbances: nausea, vomiting, or diarrhea

• Allergic reactions: rash, itching, urticaria, and rarely anaphylaxis

• Hematologic changes: transient eosinophilia, neutropenia, or thrombocytopenia in prolonged use

• Rare liver enzyme elevation or biliary sludging

Seek immediate medical attention if severe allergic reactions, persistent diarrhea, jaundice, or unusual bleeding occur.

Storage

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Dicephin Injection 500 mg/vial provides potent and broad-spectrum antibacterial therapy for moderate to severe infections, offering reliable and rapid clinical response under professional supervision.