Dulox Tablet 30 mg contains Duloxetine Hydrochloride, a selective serotonin and norepinephrine reuptake inhibitor (SNRI) used to manage depression, anxiety disorders, and chronic pain conditions. This oral tablet formulation is designed for precise dosing and consistent therapeutic effect, making it suitable for adults requiring effective control of mood disorders and pain associated with neuropathy or musculoskeletal conditions.

Duloxetine acts on the central nervous system by enhancing the levels of serotonin and norepinephrine, which play critical roles in mood regulation and pain perception. It is widely prescribed for patients with major depressive disorder (MDD), generalized anxiety disorder (GAD), diabetic peripheral neuropathy, and chronic musculoskeletal pain, including lower back pain and osteoarthritis-related discomfort.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Duloxetine Hydrochloride: 30 mg per tablet

Indications

Dulox Tablet 30 mg is indicated for:

• Major depressive disorder (MDD) in adults

• Generalized anxiety disorder (GAD)

• Diabetic peripheral neuropathic pain

• Chronic musculoskeletal pain, such as lower back pain or osteoarthritis

• Management of fibromyalgia-related pain in selected patients

• Adjunct therapy for conditions requiring dual symptom control for mood and pain

Mechanism of Action

Duloxetine exerts its therapeutic effects through dual reuptake inhibition of serotonin (5-HT) and norepinephrine (NE) in the central nervous system:

1. Serotonin reuptake inhibition: Increases serotonin levels in synapses, improving mood, reducing anxiety, and enhancing emotional stability.

2. Norepinephrine reuptake inhibition: Increases norepinephrine availability, which contributes to analgesic effects and alertness.

3. Central pain modulation: Duloxetine acts on descending pain pathways, reducing the perception of chronic neuropathic and musculoskeletal pain.

This dual mechanism allows Dulox Tablet 30 mg to address both emotional and physical symptoms, improving overall quality of life.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The usual starting dose is 30 mg once daily, which may be gradually increased depending on patient response and tolerability. Tablets should be taken at the same time each day, with or without food, to maintain steady blood levels. Dose adjustments may be required for patients with hepatic or renal impairment, elderly patients, or those taking medications with potential interactions. Abrupt discontinuation should be avoided to prevent withdrawal symptoms such as dizziness, irritability, or nausea.

Benefits of Dulox Tablet 30 mg

• Effective for treating depression and anxiety disorders

• Provides relief from neuropathic and chronic musculoskeletal pain

• Dual-action SNRI supports both mood and pain management

• Oral tablet ensures convenient once-daily dosing

• Enhances daily functioning and overall well-being

• Well-tolerated when used under medical supervision

Precautions and Warnings

• Use only under medical supervision

• Not recommended for patients with hypersensitivity to Duloxetine

• Caution in patients with liver or kidney impairment, uncontrolled hypertension, or cardiac conditions

• May increase the risk of suicidal thoughts in adolescents and young adults; close monitoring required

• Avoid abrupt discontinuation to prevent withdrawal symptoms

• Potential drug interactions with MAO inhibitors, other antidepressants, anticoagulants, or CNS-acting drugs

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Selective Serotonin and Norepinephrine Reuptake Inhibitor (SNRI) / Antidepressant.