Duocard Tablet 10 mg contains Cilnidipine, a long-acting calcium channel blocker (CCB) primarily used for the management of hypertension (high blood pressure). This oral tablet formulation provides effective blood pressure control by relaxing vascular smooth muscles, reducing systemic vascular resistance, and improving blood flow.

Cilnidipine is a dual L-type and N-type calcium channel blocker, offering unique benefits in cardiovascular protection. By selectively inhibiting calcium influx in vascular smooth muscles and sympathetic nerve endings, Duocard Tablet helps lower blood pressure while minimizing reflex tachycardia. This makes it well-suited for long-term hypertension management and patients with comorbid cardiovascular or renal conditions.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Cilnidipine: 10 mg per tablet

Indications

Duocard Tablet 10 mg is indicated for:

• Essential hypertension: To lower elevated blood pressure and reduce the risk of cardiovascular complications

• Hypertensive patients with renal involvement: Helps protect kidney function

• Management of angina pectoris associated with high blood pressure

• As part of combination therapy with other antihypertensive agents for better blood pressure control

• Prevention of cardiovascular events such as stroke or myocardial infarction in high-risk patients

Mechanism of Action

Cilnidipine works through a dual mechanism:

1. L-type calcium channel blockade: Relaxes arterial smooth muscles, reducing peripheral resistance and lowering blood pressure.

2. N-type calcium channel blockade: Inhibits sympathetic nerve activity, preventing reflex tachycardia and improving renal perfusion.

3. End-organ protection: Reduces cardiac workload and protects kidneys by maintaining effective blood flow and minimizing vascular stress.

This unique dual action differentiates Duocard from conventional calcium channel blockers, providing effective hypertension control with fewer side effects.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The typical starting dose is 10 mg once daily, which may be adjusted according to patient response and tolerance. Tablets should be taken at the same time each day, with or without food, to maintain steady blood levels. Dose adjustments may be required for patients with hepatic or renal impairment. Continuous monitoring of blood pressure is recommended during therapy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Benefits of Duocard Tablet 10 mg

• Effectively reduces high blood pressure and cardiovascular risk

• Minimizes reflex tachycardia compared to other calcium channel blockers

• Provides dual L-type and N-type calcium channel blockade for better vascular and renal protection

• Improves end-organ health, including heart and kidneys

• Convenient once-daily dosing improves adherence

• Well-tolerated for long-term therapy under medical supervision

Precautions and Warnings

• Use only under medical supervision

• Contraindicated in patients with severe hypotension, cardiogenic shock, or known hypersensitivity to Cilnidipine

• Caution in patients with liver impairment or significant heart disease

• Monitor blood pressure and heart rate regularly

• Report side effects such as dizziness, headache, flushing, or palpitations

• Avoid abrupt discontinuation to prevent rebound hypertension

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Calcium Channel Blocker / Antihypertensive.