Duocard Tablet 5 mg contains Cilnidipine, a long-acting calcium channel blocker (CCB) used for the treatment of hypertension (high blood pressure). This oral tablet formulation is designed for precise dose management, making it suitable for patients who require lower initial doses or careful titration of antihypertensive therapy.

Cilnidipine is a dual L-type and N-type calcium channel blocker, providing effective blood pressure reduction with minimal reflex tachycardia. By selectively relaxing vascular smooth muscles and inhibiting sympathetic nerve activity, Duocard Tablet helps improve blood flow, reduce cardiac workload, and protect end organs such as the heart and kidneys.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Cilnidipine: 5 mg per tablet

Indications

Duocard Tablet 5 mg is indicated for:

• Essential hypertension in adults to lower elevated blood pressure and prevent cardiovascular complications

• Patients requiring dose titration due to sensitivity or risk of hypotension

• Hypertensive patients with renal involvement to maintain kidney function

• Management of angina pectoris associated with high blood pressure

• As part of combination therapy with other antihypertensive agents for improved control

Mechanism of Action

Cilnidipine works through a dual mechanism to control blood pressure:

1. L-type calcium channel blockade: Relaxes arterial smooth muscles, decreasing peripheral resistance and reducing blood pressure.

2. N-type calcium channel blockade: Reduces sympathetic nerve activity, minimizing reflex tachycardia and improving renal perfusion.

3. End-organ protection: Supports cardiovascular and renal health by reducing vascular stress and maintaining adequate blood flow.

This dual action ensures effective and well-tolerated blood pressure control, even in sensitive patients or those requiring careful titration.

Dosage and Administration

• Route: Oral

• Dosage: As prescribed by a registered physician

The usual starting dose is 5 mg once daily, which may be adjusted depending on blood pressure response and patient tolerance. Tablets should be taken at the same time every day, with or without food, for consistent blood levels. Dose modifications may be required for patients with hepatic or renal impairment. Regular blood pressure monitoring is recommended to ensure therapeutic efficacy and safety.

Benefits of Duocard Tablet 5 mg

• Effectively reduces high blood pressure and cardiovascular risk

• Minimizes reflex tachycardia compared to conventional calcium channel blockers

• Dual L-type and N-type action supports vascular and renal protection

• Provides safe dose titration for sensitive patients or those starting therapy

• Convenient once-daily oral dosing for improved adherence

• Well-tolerated for long-term hypertension management

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use only under medical supervision

• Contraindicated in patients with severe hypotension, cardiogenic shock, or hypersensitivity to Cilnidipine

• Exercise caution in patients with heart failure, liver disease, or significant cardiac conditions

• Monitor blood pressure and heart rate during therapy

• Report side effects such as dizziness, headache, flushing, or palpitations

• Avoid abrupt discontinuation to prevent rebound hypertension

Storage Conditions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Pharmaceutical Category

Calcium Channel Blocker / Antihypertensive.