Efodio Tablet 10 mg contains Domperidone Maleate, a gastroprokinetic and antiemetic medication widely used to manage nausea, vomiting, and disorders related to delayed gastric emptying. It works by enhancing gastrointestinal motility and accelerating the transit of food through the stomach and intestines, providing symptomatic relief from digestive discomfort.

Domperidone is a dopamine D2 receptor antagonist that acts primarily on the gastrointestinal tract. By blocking dopamine receptors in the gut and chemoreceptor trigger zone, Efodio helps reduce nausea and vomiting while promoting faster gastric emptying. Unlike some other antiemetic agents, Domperidone does not readily cross the blood-brain barrier, which reduces the risk of central nervous system side effects such as drowsiness or sedation.

Efodio Tablet 10 mg is commonly prescribed for conditions such as gastroparesis, functional dyspepsia, nausea and vomiting associated with medications, post-surgical gastrointestinal discomfort, and other gastrointestinal motility disorders. It may also be used as supportive therapy in acid reflux or gastroesophageal reflux disease (GERD) when delayed gastric emptying contributes to symptoms.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Gastroprokinetic Agent

• Anti-nausea and Anti-vomiting Medication

Composition

Each tablet contains:

• Domperidone Maleate: 10 mg

This dosage provides effective relief of gastrointestinal symptoms while maintaining a favorable safety profile.

Indications

Efodio Tablet 10 mg is indicated for:

• Nausea and vomiting due to gastrointestinal disorders, medications, or surgery

• Gastroparesis and delayed gastric emptying

• Functional dyspepsia with bloating, fullness, or discomfort

• Supportive management in GERD or reflux symptoms

• Relief of vomiting caused by chemotherapy or other drugs (under physician guidance)

It is suitable for adult patients and may be used short-term to manage acute symptoms.

Mechanism of Action

Domperidone works through multiple mechanisms:

• Dopamine D2 receptor antagonism: Blocks dopamine receptors in the gastrointestinal tract and chemoreceptor trigger zone

• Enhances gastric motility: Increases peristaltic activity and accelerates gastric emptying

• Reduces nausea and vomiting: By inhibiting signals in the chemoreceptor trigger zone

• Minimal central effects: Does not significantly cross the blood-brain barrier, limiting sedation and CNS-related side effects

This dual action on motility and the vomiting reflex makes Efodio effective in various gastrointestinal and nausea-related conditions.

Dosage and Administration

• Recommended dose: 10 mg, 3 times daily before meals, or as directed by a physician

• Swallow tablets whole with water

• Use the lowest effective dose for the shortest duration necessary to relieve symptoms

• Adjust dosage for patients with severe renal or hepatic impairment under medical supervision

Possible Side Effects

Efodio Tablet 10 mg is generally well tolerated. Possible side effects include:

• Dry mouth

• Abdominal cramps or discomfort

• Diarrhea or constipation

• Headache

• Rarely, cardiac effects such as palpitations

Patients should consult a healthcare professional if side effects are persistent or severe.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Avoid in patients with known hypersensitivity to Domperidone

• Use cautiously in patients with cardiac arrhythmias, electrolyte imbalance, or liver disease

• Not recommended for long-term use unless under strict medical supervision

• Avoid use in pregnancy and breastfeeding unless clearly indicated by a physician

• Monitor for signs of extrapyramidal symptoms in rare cases

Storage

• Store in a cool, dry place below 30°C

• Protect from light and moisture

• Keep out of reach of children.