Fixcef Tablet 500 mg contains Cefuroxime Axetil, a second-generation cephalosporin antibiotic used for the treatment of a wide range of bacterial infections. It works by inhibiting bacterial cell wall synthesis, leading to the destruction of susceptible bacteria. This higher-strength formulation is commonly prescribed for moderate to severe infections.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fixcef Tablet 500 mg is indicated for the treatment of:

• Upper respiratory tract infections (sinusitis, pharyngitis, tonsillitis)
• Lower respiratory tract infections (bronchitis, pneumonia)
• Otitis media (middle ear infections)
• Urinary tract infections (UTIs)
• Skin and soft tissue infections
• Gonorrhea (uncomplicated cases, as prescribed)

Mechanism of Action

Cefuroxime Axetil is a prodrug that converts to active cefuroxime in the body. It works by:

• Inhibiting bacterial cell wall synthesis
• Binding to penicillin-binding proteins (PBPs)
• Causing bacterial cell lysis
• Eliminating susceptible bacteria effectively

It provides broad-spectrum activity against many gram-positive and gram-negative organisms.

Dosage and Administration

• Usual dose: 500 mg twice daily or as prescribed by a physician
• Take after food for better absorption
• Swallow tablet whole with water
• Do not crush or chew
• Complete the full prescribed course even if symptoms improve early

Benefits

• Broad-spectrum antibiotic for moderate to severe infections
• Effective against respiratory, urinary, ENT, and skin infections
• Well-established cephalosporin with proven efficacy
• Convenient oral dosing
• Helps prevent complications from untreated bacterial infections

Possible Side Effects

Common side effects may include:

• Diarrhea
• Nausea or vomiting
• Abdominal pain
• Headache
• Skin rash

Less common but serious side effects:

• Severe allergic reactions
• Antibiotic-associated colitis (C. difficile infection)
• Liver enzyme abnormalities

Seek medical attention if severe symptoms occur.

Precautions and Warnings

• Not effective against viral infections such as cold or flu
• Use cautiously in patients with penicillin or cephalosporin allergy
• Dose adjustment may be required in kidney impairment
• Complete full antibiotic course
• Use only under medical supervision

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Fixcef Tablet may interact with:

• Probenecid (may increase cefuroxime levels)
• Anticoagulants such as warfarin
• Other antibiotics

Always inform your healthcare provider about all medicines being used.

Storage

• Store below 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children.