Fluclox Injection 250 mg/vial contains Flucloxacillin Sodium, a narrow-spectrum penicillin antibiotic formulated for parenteral use. It is highly effective against Gram-positive bacteria, particularly Staphylococcus aureus, including penicillinase-producing strains.

This injectable form is ideal for patients who cannot take oral medications or require rapid therapeutic levels in moderate to severe bacterial infections. Flucloxacillin works by inhibiting bacterial cell wall synthesis, leading to bacterial lysis and elimination of infection.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Indications

Fluclox Injection is indicated for the treatment of:

• Severe skin and soft tissue infections (cellulitis, abscesses)
• Wound infections
• Bone and joint infections (osteomyelitis)
• Respiratory tract infections (pneumonia, tonsillitis)
• Ear infections (otitis media)
• Prophylactic use in surgeries at risk of Staphylococcus infection

Dosage and Administration

• Administered by intramuscular (IM) or intravenous (IV) injection under medical supervision.
• Adults: 250–500 mg every 6 hours, depending on infection severity.
• Pediatric doses are calculated based on body weight and clinical condition.
• Reconstitute the vial with sterile water or suitable diluent before administration.
• Infuse slowly for IV administration; IM injections should be given deeply into muscle tissue.
• Complete the full course as prescribed for optimal outcomes.

Mechanism of Action

Flucloxacillin is a beta-lactam antibiotic that:

• Binds to penicillin-binding proteins (PBPs)
• Inhibits bacterial cell wall synthesis
• Leads to bacterial lysis and death

It is particularly effective against penicillinase-producing Staphylococcus aureus, ensuring rapid and effective infection control.

Precautions

• Use cautiously in patients with a history of penicillin allergy.
• Monitor liver and kidney function during prolonged therapy.
• Prolonged therapy may result in superinfection by resistant organisms.
• Ensure adequate hydration during treatment to prevent renal complications.

Contraindications

Fluclox Injection should not be used in:

• Patients allergic to penicillin or other beta-lactam antibiotics
• Individuals with a history of severe hypersensitivity to Flucloxacillin

Side Effects

Common side effects:

• Pain or irritation at the injection site
• Nausea and vomiting
• Diarrhea
• Skin rash

Rare but serious side effects:

• Severe allergic reactions (anaphylaxis, angioedema)
• Liver dysfunction or cholestatic jaundice
• Severe diarrhea due to Clostridium difficile infection

Seek immediate medical attention if serious adverse effects occur.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

• May interact with oral anticoagulants (e.g., warfarin)
• Probenecid may reduce renal excretion and increase plasma levels
• Live bacterial vaccines may be less effective

Always inform your healthcare provider of all medications being taken.

Storage

• Store below 25–30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children
• Use reconstituted solution immediately or as advised.