Folinic Injection 10 mg/ml contains Folinic Acid, a reduced form of folic acid (vitamin B9), used to prevent or treat folate deficiency, especially in patients receiving methotrexate therapy or chemotherapy. Folinic acid helps protect healthy cells from the toxic effects of certain medications and supports DNA synthesis, repair, and red blood cell production.

This injectable formulation allows for rapid and precise administration, especially in patients who cannot take oral folic acid.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each ml contains:

• Folinic Acid 10 mg

Mechanism of Action

Folinic acid works by:

• Bypassing the metabolic step blocked by methotrexate, restoring folate availability in cells

• Supporting DNA and RNA synthesis

• Reducing hematologic and gastrointestinal toxicity associated with certain chemotherapy or antifolate drugs

• Assisting in red blood cell formation and cell repair

Indications

Folinic Injection is indicated for:

• Leucovorin rescue in patients receiving high-dose methotrexate

• Prevention and treatment of folate deficiency

• Treatment of megaloblastic anemia due to folate deficiency

• Supportive therapy in certain chemotherapy protocols

• Pediatric and adult patients unable to tolerate oral folic acid

Dosage and Administration

• Administered intravenously or intramuscularly as prescribed by a physician

• Dosage depends on patient condition, chemotherapy regimen, and severity of folate deficiency

• Follow the treatment schedule carefully for maximum efficacy

• Monitor blood counts and response during therapy

Precautions

• Use under medical supervision, especially in patients receiving chemotherapy

• Allergic reactions to folinic acid are rare but possible

• Adjust dose in renal impairment

• Not a substitute for vitamin B12 therapy in B12 deficiency

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects:

• Mild nausea or vomiting

• Redness or pain at the injection site

• Fever or chills (rare)

Serious but rare side effects:

• Allergic reactions including rash, itching, or difficulty breathing

• Rapid infusion may cause hypotension or flushing

Seek immediate medical attention if severe reactions occur.

Storage

• Store below 25°C in a cool, dry place

• Protect from light

• Keep out of reach of children

Folinic Injection 10 mg/ml is an essential supportive therapy in chemotherapy and folate-deficiency conditions, providing rapid and effective folate supplementation under medical supervision.