Gembine Injection 200 mg/5.26 ml contains Gemcitabine. It is an anticancer medicine used in hospital settings under strict medical supervision. It works by stopping the growth and multiplication of cancer cells.
This injection is part of chemotherapy regimens and is administered intravenously by trained healthcare professionals.
রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন
Composition
Each vial contains:
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Gemcitabine 200 mg in 5.26 ml solution
For intravenous (IV) infusion only.
Mechanism of Action
Gemcitabine works by:
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Inhibiting DNA synthesis in rapidly dividing cells
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Incorporating into cancer cell DNA and stopping replication
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Blocking tumor cell growth and inducing cell death
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Acting primarily on cells in the S-phase of the cell cycle
Because cancer cells divide rapidly, they are more affected than normal cells.
Indications
Gembine Injection is indicated for the treatment of:
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Non-Small Cell Lung Cancer
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Pancreatic Cancer
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Bladder Cancer
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Ovarian cancer (in combination therapy)
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Breast cancer (in selected regimens)
Dosage and Administration
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Administered intravenously by a healthcare professional only
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Dose depends on body surface area, cancer type, and treatment protocol
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Given in cycles with rest periods in between
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Should not be self-administered
Benefits
Gembine Injection provides:
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Effective inhibition of cancer cell growth
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Useful in multiple types of solid tumors
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Often used in combination chemotherapy regimens
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Helps slow disease progression
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Improves survival outcomes in certain cancers
Possible Side Effects
Common side effects include:
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Nausea and vomiting
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Fatigue
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Hair loss
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Loss of appetite
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Fever
Less common side effects:
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Low white blood cell count (leukopenia)
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Low platelet count (thrombocytopenia)
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Liver enzyme elevation
Serious side effects (require medical attention):
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Myelosuppression
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Severe infections due to weakened immunity
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Lung inflammation (interstitial pneumonitis)
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Kidney or liver toxicity
Precautions
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Must be given only under oncology supervision
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Regular blood tests are required during therapy
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Use cautiously in patients with liver, kidney, or bone marrow problems
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Avoid during pregnancy and breastfeeding
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Report fever, bleeding, or unusual fatigue immediately
Drug Interactions
Gemcitabine may interact with:
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Other chemotherapy agents
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Radiation therapy (increased toxicity risk)
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Drugs affecting bone marrow function
Storage
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Store at controlled room temperature as directed
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Protect from light
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Do not freeze
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Use only prepared solution as instructed by healthcare staff