Hemorise Injection 1 gm/20 ml is a high-dose intravenous iron formulation containing Ferric Carboxymaltose, designed for the rapid and effective treatment of iron deficiency and iron deficiency anemia in adults and children who cannot tolerate oral iron therapy or require immediate iron replenishment. This advanced formulation allows the administration of a full gram of iron in a single infusion, making it convenient for patients and healthcare providers.

Iron deficiency is a widespread cause of anemia, fatigue, impaired cognitive function, and reduced physical capacity. Hemorise Injection provides a bioavailable source of iron essential for hemoglobin synthesis, oxygen transport, and cellular metabolism. Its controlled-release profile ensures safe delivery of high-dose iron while minimizing the risk of free iron-related toxicity.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each 20 ml vial contains:

• Ferric Carboxymaltose 1 gm

Ferric Carboxymaltose is a stable iron complex that releases iron in a controlled manner, enabling rapid restoration of iron stores with minimal adverse effects.

Mechanism of Action

Ferric Carboxymaltose acts as a direct source of iron for the body. Following intravenous administration:

• The iron is absorbed by the reticuloendothelial system.

• Iron binds to transferrin, the plasma protein responsible for iron transport.

• Transferrin delivers iron to the bone marrow, where it is incorporated into hemoglobin, supporting red blood cell production.

• Controlled release minimizes free iron in the circulation, reducing oxidative stress and adverse reactions.

This mechanism allows for rapid correction of iron deficiency and improvement in hemoglobin levels while maintaining safety.

Indications

Hemorise Injection 1 gm/20 ml is indicated for:

• Iron deficiency anemia in adults and children (≥14 years) requiring rapid iron replenishment

• Patients who cannot tolerate or respond to oral iron therapy

• Management of anemia in chronic diseases where oral supplementation is insufficient

• Pre- and post-operative anemia requiring efficient correction of iron stores

Benefits

• Provides rapid and effective correction of iron deficiency

• High-dose single infusion reduces hospital visits and improves patient adherence

• Minimizes gastrointestinal side effects compared to oral iron supplements

• Supports faster recovery from anemia, enhancing energy, cognition, and physical performance

• Suitable for patients with chronic conditions such as chronic kidney disease, inflammatory bowel disease, or post-surgical anemia

Dosage and Administration

Hemorise Injection should be administered intravenously under medical supervision. The recommended single dose is 1 gm diluted in 250 ml of 0.9% sodium chloride solution, infused over at least 15–20 minutes. Additional doses may be administered based on the patient’s total iron deficit and hemoglobin response, as determined by a healthcare professional.

During administration, monitor for hypersensitivity reactions, hypotension, or other adverse events. Emergency measures for anaphylaxis should be readily available.

Precautions

• Administer only under supervision of a healthcare professional trained in managing hypersensitivity reactions.

• Monitor for signs of allergic reactions during and after infusion.

• Not recommended in patients with iron overload or hemochromatosis.

• Use with caution in patients with a history of hypersensitivity to intravenous iron preparations.

• Calculate total iron requirements before administration to avoid overdose.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Mild headache, dizziness, or nausea

• Injection site reactions such as pain, swelling, or redness

• Transient hypotension

• Rarely, severe hypersensitivity or anaphylactic reactions

Most side effects are mild and manageable when proper infusion protocols are followed.

Storage

Store below 30°C in a cool, dry place, protected from light. Do not freeze. Keep out of reach of children.

Hemorise Injection 1 gm/20 ml provides a safe, efficient, and convenient solution for rapid correction of iron deficiency anemia, helping restore hemoglobin levels and improve overall health under medical supervision.