Humalog Mix Injection 75% + 25% is a premixed insulin formulation used to control blood sugar levels in people with diabetes. It contains a combination of rapid-acting and intermediate-acting insulin components:

• Insulin Lispro
• Insulin Lispro Protamine

This combination helps manage both immediate and long-term glucose levels in the body.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each dose contains:

• Insulin Lispro 25% (rapid-acting)
• Insulin Lispro Protamine 75% (intermediate-acting)

For subcutaneous injection only.

Mechanism of Action

Humalog Mix works through two insulin actions:

Insulin Lispro (25%)

• Starts working quickly after injection
• Helps control blood sugar spikes after meals
• Mimics natural mealtime insulin

Insulin Lispro Protamine (75%)

• Absorbed slowly over time
• Provides extended blood sugar control between meals and overnight
• Helps maintain stable glucose levels

Together, they provide both rapid and sustained glucose control.

Indications

Humalog Mix Injection is indicated for:

• Diabetes Mellitus
• Type 1 diabetes (insulin-dependent diabetes)
• Type 2 diabetes when oral medications are insufficient
• Patients requiring both basal and prandial insulin coverage

Dosage and Administration

• Administered subcutaneously (under the skin) only
• Usually injected before meals as prescribed
• Dose depends on blood glucose levels, diet, and individual needs
• Injection sites include abdomen, thigh, or upper arm
• Rotate injection sites to avoid lipodystrophy

Benefits

Humalog Mix Injection provides:

• Dual action: rapid + intermediate glucose control
• Helps control both fasting and post-meal blood sugar
• Reduces need for multiple insulin injections
• Improves overall glycemic control
• Convenient premixed formulation

Possible Side Effects

Common side effects include:

• Hypoglycemia (low blood sugar)
• Weight gain
• Injection site redness or swelling

Less common side effects:

• Lipodystrophy (fat changes at injection site)
• Mild allergic reactions
• Itching or rash

Serious side effects:

• Severe Hypoglycemia
• Severe allergic reaction (rare)

Precautions

• Monitor blood glucose regularly
• Do not skip meals after injection
• Use cautiously in kidney or liver disease
• Avoid alcohol as it may increase risk of hypoglycemia
• Always follow prescribed dosing schedule

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Drug Interactions

Humalog Mix may interact with:

• Other antidiabetic drugs (increased risk of hypoglycemia)
• Beta-blockers (may mask symptoms of low blood sugar)
• Corticosteroids (may increase blood sugar levels)

Storage

• Store in refrigerator (2°C–8°C) before use
• Do not freeze
• Once in use, may be kept at room temperature for a limited period as advised
• Protect from heat and direct sunlight