Indapa-Plus Tablet 2 mg + 1.25 mg is a fixed-dose combination antihypertensive medicine containing Perindopril 2 mg and Indapamide 1.25 mg. It is indicated for the treatment of essential hypertension in adults. This combination therapy offers a dual mechanism of action to effectively reduce elevated blood pressure and lower the risk of cardiovascular complications.

High blood pressure is often a silent condition that can lead to serious health problems such as heart attack, stroke, kidney disease, and heart failure if left untreated. Indapa-Plus Tablet helps maintain controlled blood pressure levels, contributing to long-term cardiovascular protection when used alongside lifestyle changes such as a balanced diet, reduced salt intake, regular exercise, and smoking cessation.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

Each tablet contains:

• Perindopril 2 mg

• Indapamide 1.25 mg

Mechanism of Action

Perindopril belongs to the class of angiotensin-converting enzyme (ACE) inhibitors. It works by blocking the formation of angiotensin II, a substance that causes blood vessels to constrict. By relaxing and widening blood vessels, Perindopril reduces vascular resistance and helps lower blood pressure, making it easier for the heart to pump blood.

Indapamide is a thiazide-like diuretic. It promotes the excretion of excess sodium and water through urine, which reduces blood volume and contributes to blood pressure reduction. Additionally, it has mild vasodilatory properties that enhance its antihypertensive effect.

Together, these two agents provide complementary and sustained blood pressure control.

Indications

Indapa-Plus Tablet 2 mg + 1.25 mg is indicated for:

• Essential hypertension

• Patients requiring combination therapy for blood pressure control

• Individuals not adequately controlled with monotherapy

It may be prescribed as initial therapy in certain patients or as an alternative when single-drug treatment is insufficient.

Dosage and Administration

• The usual recommended dose is one tablet once daily.

• It is generally taken in the morning, preferably before meals.

• Swallow the tablet whole with a glass of water.

• Follow the physician’s instructions carefully and do not exceed the prescribed dose.

Regular monitoring of blood pressure and laboratory parameters may be required during treatment.

Precautions

Before taking Indapa-Plus Tablet, inform your healthcare provider if you have:

• Kidney or liver impairment

• Diabetes

• Electrolyte imbalance

• History of angioedema

• Heart disease

• Gout

ACE inhibitors may cause a persistent dry cough in some individuals. Indapamide may affect electrolyte levels such as potassium and sodium; therefore, periodic blood tests are advisable.

Use in Pregnancy and Lactation

This medicine is not recommended during pregnancy due to potential harm to the developing fetus. It should also be avoided during breastfeeding unless specifically advised by a doctor.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects may include:

• Dizziness or lightheadedness

• Headache

• Dry cough

• Increased urination

• Fatigue

Serious adverse effects are rare but may include allergic reactions, significant electrolyte disturbances, or kidney function changes. Seek medical advice if unusual symptoms occur.

Storage

Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.

Indapa-Plus Tablet 2 mg + 1.25 mg provides effective dual-action blood pressure management and supports long-term cardiovascular health when used under proper medical supervision.