Intracef Capsule 250 mg contains Cephradine, a first-generation cephalosporin antibiotic used to treat a wide range of bacterial infections. It is effective against many gram-positive and some gram-negative organisms. Intracef Capsule is commonly prescribed for infections of the respiratory tract, urinary tract, skin, and soft tissues, as well as other susceptible infections. Its proven efficacy, good safety profile, and oral convenience make it a reliable option in everyday clinical practice.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Cephalosporin Antibiotics
Beta-lactam Antibacterial Agent

Composition

Each capsule contains Cephradine 250 mg.

Indications

Intracef Capsule 250 mg is indicated for the treatment of the following infections caused by susceptible organisms:

• Upper and lower respiratory tract infections, including tonsillitis, pharyngitis, bronchitis, and pneumonia

• Urinary tract infections

• Skin and soft tissue infections

• Ear, nose, and throat infections

• Bone and joint infections

• Other mild to moderate bacterial infections as determined by the physician

It may be used when oral antibiotic therapy is appropriate and the causative organisms are sensitive to cephradine.

Pharmacology

Cephradine is a bactericidal antibiotic that works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins within the bacterial cell wall, leading to cell lysis and death of the organism. Cephradine is stable in the presence of many beta-lactamases produced by bacteria, which enhances its antibacterial activity. After oral administration, it is well absorbed from the gastrointestinal tract and achieves therapeutic concentrations in various body tissues and fluids.

Dosage and Administration

The dosage of Intracef Capsule 250 mg depends on the type and severity of infection, patient age, and renal function.

• Typically administered in divided doses throughout the day

• Capsules should be swallowed whole with sufficient water

The duration of therapy should be determined by a healthcare professional, and the full prescribed course should be completed to prevent antibiotic resistance.

Contraindications

Intracef Capsule 250 mg is contraindicated in patients with:

• Known hypersensitivity to cephradine or other cephalosporin antibiotics

• History of severe allergic reactions to beta-lactam antibiotics

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with renal impairment; dose adjustment may be required

• Patients with a history of penicillin allergy should be monitored closely due to possible cross-sensitivity

• Prolonged use may result in overgrowth of non-susceptible organisms

Adverse Effects

Intracef Capsule 250 mg is generally well tolerated. Possible adverse effects include:

• Nausea

• Vomiting

• Diarrhea

• Abdominal discomfort

• Skin rash or allergic reactions

Most side effects are mild and reversible upon discontinuation.

Drug Interactions

Cephradine should be used cautiously with:

• Other nephrotoxic drugs

• Oral anticoagulants, as monitoring may be required

Always inform the healthcare provider about all concomitant medications.

Storage

Store in a cool and dry place, away from light and moisture. Keep out of reach of children.

Conclusion

Intracef Capsule 250 mg is an effective oral cephalosporin antibiotic offering reliable treatment for a variety of bacterial infections. With its broad-spectrum activity, good tolerability, and convenient dosing, it remains a trusted choice for managing mild to moderate infections in clinical practice.