Intracef Suspension 125 mg/5 ml contains Cephradine, a first-generation cephalosporin antibiotic formulated as an oral suspension. This pediatric-friendly dosage form is designed for infants and children who have difficulty swallowing capsules or tablets. Intracef Suspension is effective in the treatment of a wide range of mild to moderate bacterial infections caused by susceptible organisms and is commonly used in routine pediatric and general clinical practice.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

Cephalosporin Antibiotics
Beta-lactam Antibacterial Agent

Composition

Each 5 ml of reconstituted suspension contains Cephradine 125 mg.

Indications

Intracef Suspension 125 mg/5 ml is indicated for the treatment of infections caused by susceptible bacteria, including:

• Upper and lower respiratory tract infections such as tonsillitis, pharyngitis, bronchitis, and pneumonia

• Ear, nose, and throat infections including otitis media and sinusitis

• Urinary tract infections

• Skin and soft tissue infections

• Bone and joint infections

This suspension is particularly suitable for pediatric patients and for adults who prefer liquid formulations.

Pharmacology

Cephradine is a bactericidal cephalosporin antibiotic that acts by inhibiting bacterial cell wall synthesis. It binds to specific penicillin-binding proteins, preventing proper formation of the bacterial cell wall and leading to cell lysis and death. Cephradine is stable against many beta-lactamases, allowing it to retain activity against a broad range of common pathogens. Following oral administration, it is well absorbed and distributes effectively into body tissues and fluids.

Dosage and Administration

The dosage of Intracef Suspension 125 mg/5 ml depends on the patient’s age, body weight, severity of infection, and renal function.

• The suspension should be reconstituted as directed before use

• Shake well before each dose to ensure uniform distribution

• Administer the prescribed dose at regular intervals

The full course of therapy should be completed to prevent recurrence of infection and development of resistance.

Contraindications

Intracef Suspension 125 mg/5 ml is contraindicated in patients with:

• Known hypersensitivity to cephradine or other cephalosporin antibiotics

• History of severe allergic reactions to beta-lactam antibiotics

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Precautions and Warnings

• Use with caution in patients with renal impairment; dosage adjustment may be necessary

• Patients with a history of penicillin allergy should be monitored carefully due to possible cross-reactivity

• Prolonged use may lead to overgrowth of non-susceptible organisms

Adverse Effects

Intracef Suspension is generally well tolerated. Possible side effects include:

• Nausea

• Diarrhea

• Vomiting

• Abdominal discomfort

• Skin rash or allergic reactions

Most adverse effects are mild and reversible.

Drug Interactions

Caution is advised when used with:

• Nephrotoxic medicines

• Oral anticoagulants, which may require monitoring

Storage

Store the dry powder in a cool and dry place. After reconstitution, store as directed and use within the recommended time. Keep out of reach of children.

Conclusion

Intracef Suspension 125 mg/5 ml is a reliable and effective oral cephalosporin antibiotic, especially suitable for pediatric patients. Its broad antibacterial coverage, good tolerability, and convenient liquid formulation make it an important option for treating common bacterial infections.