Ipratop Respirator Solution 250 mcg/ml contains Ipratropium Bromide, a bronchodilator belonging to the class of anticholinergic agents. It is used in the management of chronic respiratory conditions such as chronic obstructive pulmonary disease (COPD), chronic bronchitis, and asthma, where it helps relieve bronchospasm and improve airflow. Ipratop acts by relaxing the muscles around the airways, allowing easier breathing. This solution is intended for inhalation via nebulizer or other respiratory delivery devices.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Therapeutic Class

• Bronchodilators

• Anticholinergic agents

Composition

Each milliliter of Ipratop Respirator Solution contains:

• Ipratropium Bromide 250 mcg

Indications

Ipratop Respirator Solution is indicated for:

• Maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD)

• Symptomatic relief of chronic bronchitis and emphysema

• Adjunct therapy for asthma to relieve airway obstruction

• Prevention and management of exercise-induced bronchospasm in certain cases

• Management of bronchospasm in acute exacerbations

The solution provides targeted bronchodilation and is often combined with other therapies such as beta-agonists for enhanced symptom control.

Pharmacology

Ipratropium Bromide is a short-acting anticholinergic agent that works by inhibiting muscarinic receptors in the airways. This prevents acetylcholine-induced bronchoconstriction and reduces mucus secretion in the respiratory tract. The resulting relaxation of airway smooth muscles improves airflow, reduces wheezing, and alleviates shortness of breath. Ipratropium has minimal systemic absorption, which limits side effects and enhances safety during long-term therapy.

Dosage and Administration

Adults and Adolescents (≥12 years):

• Nebulizer solution: 500 mcg (2 ml of 250 mcg/ml solution) 3–4 times daily

• Administer via nebulizer with oxygen or compressed air at 6–8 liters/min for 5–15 minutes

Children (6–12 years):

• 250–500 mcg via nebulizer 3–4 times daily

Elderly:

• Same dosage as adults; adjust based on response

Administration Notes:

• Shake the solution well before use

• Use a clean nebulizer to ensure proper delivery

• Do not mix with other nebulizer solutions unless prescribed by a physician

• Rinse mouth after inhalation to reduce dry mouth and throat irritation

Contraindications

• Known hypersensitivity to Ipratropium Bromide or atropine derivatives

• Avoid in patients with a history of severe allergy to peanuts or soy lecithin if present in the formulation

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Common adverse reactions include:

• Dry mouth or throat

• Cough

• Bitter taste

• Mild dizziness or headache

Rare side effects may include:

• Palpitations

• Urinary retention

• Eye irritation if the solution contacts the eyes

Drug Interactions

• Minimal systemic interactions due to poor absorption

• Concomitant use with other inhaled bronchodilators is generally safe and may be synergistic

• Exercise caution with anticholinergic drugs due to additive effects

Pregnancy and Lactation

• Use only if clearly needed and prescribed by a physician

• Limited data in pregnancy; benefits must outweigh risks

• Use caution during breastfeeding; monitor the infant for potential anticholinergic effects

Precautions and Warnings

• Not intended for relief of acute asthma attacks; use a short-acting beta-agonist in emergencies

• Use with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, or bladder obstruction

• Regular monitoring is recommended for long-term therapy

Storage Conditions

• Store below 25°C, protected from light

• Keep out of reach of children

• Do not freeze the solution.