Labecard Injection 50 mg/10 ml contains Labetalol Hydrochloride, a combined alpha- and beta-adrenergic blocker used for the rapid control of high blood pressure (hypertension), especially in emergency situations. It is commonly administered in hospital settings for the management of hypertensive crises, severe hypertension during pregnancy, and perioperative blood pressure control.

This injectable formulation provides a fast and controlled reduction in blood pressure, making it a preferred choice in critical care and emergency medicine.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Labetalol Hydrochloride
• Strength: 50 mg per 10 ml
• Dosage Form: Sterile injection

Mechanism of Action

Labetalol works by blocking both alpha-1 and beta-adrenergic receptors. This dual action leads to:

• Reduction in peripheral vascular resistance (via alpha-blockade)
• Decrease in heart rate and cardiac output (via beta-blockade)

As a result, it effectively lowers blood pressure without significantly reducing blood flow to vital organs.

Indications

Labecard Injection is indicated for:

• Hypertensive emergencies
• Severe hypertension
• Hypertension during pregnancy (including preeclampsia)
• Control of blood pressure during surgery (perioperative hypertension)
• Acute management of high blood pressure in hospitalized patients

Dosage and Administration

• Administered intravenously (IV) by healthcare professionals
• Can be given as a slow IV injection or continuous infusion
• Initial dose typically starts at 20 mg IV, followed by incremental doses if needed
• Dosage should be individualized based on patient response and clinical condition
• Continuous monitoring of blood pressure and heart rate is essential

Benefits

• Rapid and effective blood pressure control
• Dual mechanism enhances antihypertensive effect
• Suitable for emergency and critical care use
• Safe option in pregnancy-related hypertension
• Maintains stable blood flow to vital organs

Side Effects

Common side effects may include:

• Dizziness or lightheadedness
• Fatigue
• Nausea
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)

Rare but serious side effects:

• Bronchospasm (especially in asthmatic patients)
• Heart block or worsening heart failure
• Severe allergic reactions

Precautions and Warnings

• Use under strict medical supervision
• Monitor blood pressure and heart rate continuously
• Use with caution in patients with asthma, heart failure, or liver disease
• Avoid abrupt discontinuation
• Not recommended in patients with severe bradycardia or heart block

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Use in Special Populations

• Pregnancy: Commonly used and considered relatively safe under medical guidance
• Lactation: Consult a healthcare provider before use
• Pediatrics: Use only if prescribed
• Elderly: Dose adjustment and close monitoring may be required

Storage

• Store below 25°C
• Protect from light
• Do not freeze
• Keep out of reach of children.