Leroid Tablet 50 mcg contains Levothyroxine Sodium, a synthetic form of the thyroid hormone thyroxine (T4), used to treat hypothyroidism and related thyroid disorders. Hypothyroidism is a condition where the thyroid gland produces insufficient thyroid hormones, leading to slowed metabolism, fatigue, weight gain, cold intolerance, and other systemic effects. Leroid Tablet 50 mcg helps restore normal hormone levels, improving metabolic function and overall health.

Levothyroxine sodium is structurally identical to endogenous thyroxine, allowing it to effectively replace the deficient hormone and maintain normal physiological processes. This tablet is indicated for long-term management and maintenance therapy in patients with thyroid hormone deficiency.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Levothyroxine acts as a thyroid hormone replacement. Its mechanism includes:

• Hormone replacement: Provides exogenous thyroxine (T4) that is converted in peripheral tissues to triiodothyronine (T3), the active form.

• Regulation of metabolism: Restores normal basal metabolic rate, protein synthesis, and energy production in cells.

• Support of growth and development: In children, Levothyroxine ensures proper growth, brain development, and skeletal maturation.

• Cardiovascular effects: Enhances cardiac output and oxygen consumption, improving systemic circulation.

By mimicking natural thyroid hormone, Levothyroxine corrects hypothyroidism and stabilizes metabolic activity throughout the body.

Indications

Leroid Tablet 50 mcg is indicated for:

• Primary hypothyroidism: Replacement therapy in adults and children with thyroid hormone deficiency.

• Secondary or tertiary hypothyroidism: When hypothyroidism is due to pituitary or hypothalamic dysfunction.

• Goiter management: Adjunct therapy for benign thyroid enlargement.

• Myxedema: Severe hypothyroidism requiring thyroid hormone replacement.

• Thyroid hormone suppression therapy: In certain thyroid cancers to reduce TSH stimulation.

Dosage and Administration

• The usual adult dose is 50 mcg once daily, taken orally on an empty stomach, preferably 30–60 minutes before breakfast.

• Tablets should be swallowed whole with a full glass of water.

• Dosage must be individualized based on age, weight, severity of hypothyroidism, and clinical response, often guided by periodic measurement of TSH (thyroid-stimulating hormone) levels.

• Children, elderly patients, and those with cardiovascular disease require careful dose titration.

Precautions

• Inform your doctor if you have heart disease, adrenal insufficiency, diabetes, or osteoporosis before starting therapy.

• Use with caution in elderly patients due to increased risk of cardiac events.

• Regular monitoring of TSH, T4, and T3 levels is recommended to ensure proper dosing.

• Abrupt discontinuation may worsen hypothyroid symptoms.

Use in Pregnancy and Lactation

• Levothyroxine is safe and recommended during pregnancy, as adequate thyroid hormone levels are essential for fetal development.

• Dose adjustments may be necessary during pregnancy due to increased thyroid hormone requirements.

• Lactation is generally safe while taking Levothyroxine, but monitoring infant thyroid function is advised.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Leroid Tablet 50 mcg is generally well tolerated when dosed appropriately. Side effects may occur if the dose is too high, including:

• Palpitations or rapid heart rate

• Nervousness, tremors, or anxiety

• Weight loss or increased appetite

• Sweating or heat intolerance

• Headache or insomnia

Severe overdose can cause thyrotoxicosis, leading to chest pain, arrhythmia, or bone loss. Seek immediate medical attention if serious symptoms occur.

Storage

Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.

Leroid Tablet 50 mcg provides safe and effective thyroid hormone replacement, helping patients with hypothyroidism achieve normal metabolic function, improved energy levels, and overall health when taken under medical supervision.