Levoflox Tablet 500 mg contains Levofloxacin Hemihydrate, a broad-spectrum fluoroquinolone antibiotic used to treat various bacterial infections. Levofloxacin is the active L-isomer of ofloxacin and is effective against a wide range of Gram-positive and Gram-negative bacteria, including respiratory, urinary, and skin pathogens.

Levoflox Tablet 500 mg works by inhibiting bacterial DNA replication, leading to rapid bacterial cell death. This oral antibiotic provides a convenient therapy option for moderate to severe infections, including community-acquired pneumonia, urinary tract infections, skin infections, and more.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Levofloxacin acts as a bactericidal antibiotic through the following mechanism:

• Inhibition of DNA gyrase and topoisomerase IV: Prevents bacterial DNA replication, transcription, and repair.

• Disruption of bacterial cell division: Leads to bacterial cell death.

• Broad-spectrum activity: Effective against both Gram-positive and Gram-negative bacteria, including resistant strains.

This mechanism makes Levoflox effective in treating infections caused by susceptible pathogens while minimizing the risk of bacterial resistance when used appropriately.

Indications

Levoflox Tablet 500 mg is indicated for the treatment of:

• Respiratory tract infections: Community-acquired pneumonia, chronic bronchitis exacerbations, and sinusitis

• Urinary tract infections: Acute pyelonephritis, complicated and uncomplicated urinary infections

• Skin and soft tissue infections: Cellulitis, abscesses, and wound infections

• Prophylaxis: In specific cases for prevention of bacterial infections in immunocompromised patients (under physician guidance)

• Other susceptible bacterial infections: As determined by culture and sensitivity testing

Levoflox is particularly useful for infections caused by E. coli, Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and other susceptible pathogens.

Dosage and Administration

• The usual adult dose for moderate infections is 500 mg once daily, orally, with or without food.

• Severe or complicated infections may require dose adjustments based on clinical response and kidney function.

• Swallow the tablet whole with a full glass of water; do not crush or chew.

• Complete the full prescribed course even if symptoms improve to prevent bacterial resistance.

• Adequate hydration is recommended to prevent crystalluria and maintain kidney function.

Precautions

• Consult your doctor if you have a history of tendon disorders, kidney disease, heart rhythm abnormalities, or neurological conditions.

• Avoid unnecessary sun exposure during therapy as Levofloxacin may increase photosensitivity.

• Caution is advised in patients taking antacids, iron, or multivitamins; these can reduce absorption.

• Not recommended for use in pregnant or breastfeeding women unless specifically prescribed.

• Monitor for signs of allergic reactions, tendon pain, or severe diarrhea, which may indicate complications like tendon rupture or Clostridioides difficile infection.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Nausea, vomiting, or diarrhea

• Headache or dizziness

• Abdominal pain

• Mild insomnia or restlessness

Rare but serious side effects include:

• Tendon rupture or tendonitis

• Peripheral neuropathy

• Severe allergic reactions

• QT interval prolongation

Patients should report persistent or severe symptoms immediately.

Storage

Store below 30°C in a dry place, protected from sunlight and moisture. Keep out of reach of children.

Levoflox Tablet 500 mg provides effective, broad-spectrum antibacterial therapy, offering convenient oral administration, rapid infection control, and improved patient outcomes under medical supervision.