Ligotin Tablet 25 mg contains Alogliptin Benzoate, a Dipeptidyl Peptidase-4 (DPP-4) inhibitor used in the management of type 2 diabetes mellitus. This oral antidiabetic medication helps control blood glucose levels by enhancing the body’s natural insulin response and reducing inappropriate glucagon secretion. Ligotin Tablet 25 mg is suitable for adults whose blood sugar is inadequately controlled with diet and exercise, and it can be used as monotherapy or in combination with other antidiabetic agents.

By prolonging the activity of incretin hormones, Ligotin helps the pancreas release insulin in response to meals and decreases excessive glucose production by the liver, improving both postprandial and fasting blood sugar levels. Its glucose-dependent mechanism minimizes the risk of hypoglycemia compared to some other oral antidiabetic agents.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Alogliptin Benzoate works as a DPP-4 inhibitor, exerting its effects through:

• Inhibition of DPP-4 enzyme: Prevents breakdown of incretin hormones such as GLP-1 and GIP.

• Enhanced insulin secretion: Stimulates pancreatic beta cells to release insulin in response to elevated glucose.

• Reduced glucagon secretion: Suppresses alpha cell activity, lowering hepatic glucose production.

• Glucose-dependent action: Increases insulin only when blood sugar is high, reducing hypoglycemia risk.

This targeted mechanism provides effective glycemic control while maintaining a favorable safety profile.

Indications

Ligotin Tablet 25 mg is indicated for:

• Type 2 diabetes mellitus: For patients inadequately controlled with diet and lifestyle measures.

• Combination therapy: Can be safely combined with metformin, sulfonylureas, or insulin to optimize blood sugar control.

• Management of postprandial hyperglycemia: Helps prevent blood sugar spikes after meals.

It is not intended for type 1 diabetes or the treatment of diabetic ketoacidosis.

Dosage and Administration

• The standard adult dose is 25 mg once daily, orally, with or without food.

• Swallow the tablet whole with water; do not crush or chew.

• Dose adjustment may be necessary in patients with renal impairment.

• Regular monitoring of blood glucose and HbA1c is recommended to assess treatment effectiveness.

• Continue adherence to diet, exercise, and lifestyle modifications for optimal results.

Precautions

• Consult your doctor if you have kidney or liver disease, pancreatitis, or a history of hypersensitivity to DPP-4 inhibitors.

• Use caution when combining with insulin or sulfonylureas, as the risk of hypoglycemia may increase.

• Report severe abdominal pain, nausea, or vomiting immediately, as these may indicate pancreatitis.

• Safety during pregnancy and lactation is not fully established; medical guidance is required.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Ligotin Tablet 25 mg is generally well tolerated. Common side effects may include:

• Upper respiratory tract infections (nasopharyngitis)

• Headache

• Mild gastrointestinal disturbances, including nausea or diarrhea

Rare but serious side effects may include:

• Pancreatitis

• Severe allergic reactions (rash, swelling, difficulty breathing)

• Severe joint pain

Patients experiencing severe or persistent symptoms should seek medical attention immediately.

Storage

Store below 30°C in a dry place, protected from direct sunlight and moisture. Keep out of reach of children.

Ligotin Tablet 25 mg provides effective and convenient oral therapy for type 2 diabetes, helping patients achieve stable blood sugar levels, support pancreatic function, and maintain long-term metabolic health under proper medical supervision.