Lofat Capsule 200 mg contains Fenofibrate, a lipid-regulating agent from the fibrate class, widely used in the management of dyslipidemia. It is particularly effective in reducing elevated triglyceride levels and improving abnormal cholesterol profiles. Lofat Capsule is prescribed as an adjunct to dietary modification and lifestyle changes to help reduce the risk of cardiovascular complications associated with high lipid levels.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Composition

• Active Ingredient: Fenofibrate

• Strength: 200 mg per capsule

Therapeutic Class

• Antihyperlipidemic agent

• Fibrate derivative

Indications

Lofat Capsule 200 mg is indicated for the treatment of:

• Hypertriglyceridemia

• Primary hypercholesterolemia

• Mixed dyslipidemia

• Lipid abnormalities not adequately controlled by diet alone

• Reduction of cardiovascular risk in patients with elevated lipid levels

It is especially beneficial in patients with high triglycerides and low HDL cholesterol.

Mechanism of Action

Fenofibrate works by activating peroxisome proliferator-activated receptor alpha (PPAR-α). Activation of this receptor enhances the breakdown and clearance of triglyceride-rich lipoproteins from the blood. Fenofibrate reduces triglycerides, lowers low-density lipoprotein (LDL) cholesterol, and increases high-density lipoprotein (HDL) cholesterol. This overall improvement in lipid profile helps slow the progression of atherosclerosis and reduces cardiovascular risk.

Dosage and Administration

• The usual recommended dose is 200 mg once daily, or as prescribed by a physician.

• Capsules should be taken with food to enhance absorption.

• Dose adjustments may be required in patients with renal impairment.

• Therapy should be combined with appropriate dietary and lifestyle measures.

Benefits

• Effectively lowers triglyceride levels

• Improves overall lipid profile

• Helps increase protective HDL cholesterol

• Reduces risk of cardiovascular complications

• Suitable for long-term lipid management under supervision

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Side Effects

Lofat Capsule is generally well tolerated. Some patients may experience:

• Gastrointestinal discomfort

• Nausea or abdominal pain

• Headache

• Mild elevation of liver enzymes

Rare but serious effects include muscle pain or weakness, which should be reported promptly.

Precautions and Warnings

• Use with caution in patients with liver or kidney impairment.

• Regular monitoring of liver function tests and lipid levels is advised.

• Not recommended in patients with severe renal disease or gallbladder disease.

• Use during pregnancy and breastfeeding only if clearly prescribed by a physician.

Storage Instructions

• Store below 30°C in a dry place

• Protect from light and moisture

• Keep out of reach of children

Conclusion

Lofat Capsule 200 mg is an effective lipid-lowering medication that plays a key role in managing dyslipidemia, particularly elevated triglyceride levels. With Fenofibrate as its active ingredient, it helps improve cholesterol balance and reduce cardiovascular risk when used alongside proper diet and lifestyle changes.