Losardil Tablet 25 mg contains Losartan Potassium, an angiotensin II receptor blocker (ARB) used primarily for the management of hypertension (high blood pressure) and for the protection of the kidneys in patients with type 2 diabetes and proteinuria. By controlling blood pressure, Losardil helps reduce the risk of stroke, heart attack, and other cardiovascular complications.

Losartan works by blocking the action of angiotensin II, a chemical in the body that causes blood vessels to constrict. This leads to relaxation of blood vessels, lowering blood pressure and improving blood flow. It also reduces the workload on the heart and helps prevent damage to the kidneys, especially in patients with diabetic nephropathy.

রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Mechanism of Action

Losardil Tablet 25 mg acts through the following mechanism:

• Angiotensin II receptor blockade: Losartan selectively blocks the AT1 receptor, preventing angiotensin II from constricting blood vessels.

• Vasodilation: Relaxed blood vessels lead to reduced systemic vascular resistance and lower blood pressure.

• Renal protection: By decreasing intraglomerular pressure, it helps reduce proteinuria and slow the progression of kidney damage in diabetic patients.

• Cardioprotective effect: Reduces strain on the heart and lowers the risk of cardiovascular events in hypertensive patients.

Through this mechanism, Losardil provides sustained blood pressure control and protection against hypertension-related complications.

Indications

Losardil Tablet 25 mg is indicated for:

• Hypertension: Monotherapy or in combination with other antihypertensive agents to control elevated blood pressure.

• Diabetic nephropathy: Slows the progression of kidney disease in patients with type 2 diabetes and proteinuria.

• Cardiovascular risk reduction: Helps reduce the risk of stroke, heart attack, and other complications associated with high blood pressure.

It is not suitable for patients with pregnancy, severe liver disease, or known hypersensitivity to Losartan.

Dosage and Administration

• The usual starting dose for adults is 25 mg once daily, which may be adjusted based on blood pressure response.

• Take the tablet orally with or without food, preferably at the same time each day.

• Monitor blood pressure, kidney function, and electrolytes regularly, especially during the initial stages of therapy.

• Dosage adjustments may be necessary in patients with renal impairment or liver disease.

• Continue lifestyle measures such as diet, exercise, and salt restriction to optimize blood pressure control.

Precautions

• Avoid use during pregnancy, as ARBs may cause fetal harm.

• Caution in patients with kidney disease, low blood pressure, or hyperkalemia (high potassium levels).

• Inform your doctor about any other medications being taken, especially potassium supplements, diuretics, or NSAIDs.

• Use with care in elderly patients, as they may be more sensitive to blood pressure-lowering effects.

  রেজিস্টার্ড চিকিৎসকের পরামর্শ অনুযায়ী ঔষধ সেবন করুন

Possible Side Effects

Common side effects include:

• Dizziness or lightheadedness, especially after the first dose

• Fatigue

• Headache

• Mild gastrointestinal symptoms such as nausea or diarrhea

Rare but serious side effects include:

• Hyperkalemia (high potassium)

• Low blood pressure (hypotension)

• Kidney function impairment

• Allergic reactions (rash, itching, swelling, difficulty breathing)

Seek immediate medical attention if severe or persistent symptoms occur.

Storage

Store below 30°C in a dry place, protected from direct sunlight and moisture. Keep out of reach of children.

Losardil Tablet 25 mg offers effective blood pressure management, renal protection, and cardiovascular risk reduction, making it an essential therapy for patients with hypertension and associated comorbidities.